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Fine-mapping the MHC locus in juvenile idiopathic arthritis (JIA) reveals genetic heterogeneity corresponding to distinct adult inflammatory arthritic diseases.
Hinks, A; Bowes, J; Cobb, J; Ainsworth, H C; Marion, M C; Comeau, M E; Sudman, M; Han, B; Becker, M L; Bohnsack, J F; de Bakker, P I W; Haas, J P; Hazen, M; Lovell, D J; Nigrovic, P A; Nordal, E; Punnaro, M; Rosenberg, A M; Rygg, M; Smith, S L; Wise, C A; Videm, V; Wedderburn, L R; Yarwood, A; Yeung, R S M; Prahalad, S; Langefeld, C D; Raychaudhuri, S; Thompson, S D; Thomson, W.
Afiliação
  • Hinks A; Arthritis Research UK Centre for Genetics and Genomics, Manchester Academic Health Science Centre, University Of Manchester, Manchester, UK.
  • Bowes J; Arthritis Research UK Centre for Genetics and Genomics, Manchester Academic Health Science Centre, University Of Manchester, Manchester, UK.
  • Cobb J; Arthritis Research UK Centre for Genetics and Genomics, Manchester Academic Health Science Centre, University Of Manchester, Manchester, UK.
  • Ainsworth HC; NIHR Manchester Musculoskeletal Biomedical Research Unit, Central Manchester University Hospitals NHS Foundation Trust, Manchester, UK.
  • Marion MC; Center for Public Health Genomics and Department of Biostatistical Sciences, Wake Forest University School of Medicine, Winston-Salem, North Carolina, USA.
  • Comeau ME; Center for Public Health Genomics and Department of Biostatistical Sciences, Wake Forest University School of Medicine, Winston-Salem, North Carolina, USA.
  • Sudman M; Center for Public Health Genomics and Department of Biostatistical Sciences, Wake Forest University School of Medicine, Winston-Salem, North Carolina, USA.
  • Han B; Center for Autoimmune Genomics and Etiology, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, USA.
  • Becker ML; Department of Convergence Medicine, University of Ulsan College of Medicine & Asan Institute for Life Sciences, Asan Medical Center, Seoul, Republic of Korea.
  • de Bakker PI; Division of Rheumatology and Division of Clinical Pharmacology, Toxicology, and Therapeutic Innovation, Children's Mercy-Kansas City, Kansas City, Missouri, USA.
  • Haas JP; Division of Allergy, Immunology and Paediatric Rheumatology, University of Utah, Salt Lake City, Utah, USA.
  • Hazen M; Department of Medical Genetics, Center for Molecular Medicine, University Medical Center Utrecht, Utrecht, The Netherlands.
  • Lovell DJ; German Center for Pediatric and Adolescent Rheumatology, Garmisch-Partenkirchen, Germany.
  • Nigrovic PA; Division of Immunology, Department of Rheumatology, Boston Children's Hospital, Boston, Massachusetts, USA.
  • Nordal E; Division of Rheumatology, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, USA.
  • Punnaro M; Division of Immunology, Department of Rheumatology, Boston Children's Hospital, Boston, Massachusetts, USA.
  • Rosenberg AM; Division of Rheumatology, Immunology and Allergy, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, USA.
  • Rygg M; Department of Paediatrics, University Hospital of North Norway, and UIT The Arctic University of Norway, Tromsø, Norway.
  • Smith SL; Arthritis Clinic Texas Scottish Rite Hospital for Children, Dallas, Texas, USA.
  • Wise CA; Department of Paediatrics, UT Southwestern Medical Center, Dallas, Texas, USA.
  • Videm V; Division of Rheumatology, Department of Paediatrics, University of Saskatchewan, Saskatoon, Canada.
  • Wedderburn LR; Department of Laboratory Medicine, Children's and Women's Health, NTNU - Norwegian University of Science and Technology, and St. Olavs University Hospital, Trondheim, Norway.
  • Yarwood A; Arthritis Research UK Centre for Genetics and Genomics, Manchester Academic Health Science Centre, University Of Manchester, Manchester, UK.
  • Yeung RS; Sarah M. and Charles E. Seay Center for Musculoskeletal Research, Texas Scottish Rite Hospital for Children, Dallas, Texas, USA.
  • Prahalad S; Department of Orthopaedic Surgery, Paediatrics, and McDermott Center for Human Growth and Development, UT Southwestern Medical Center, Dallas, Texas, USA.
  • Langefeld CD; Department of Laboratory Medicine, Children's and Women's Health, NTNU - Norwegian University of Science and Technology, and St. Olavs University Hospital, Trondheim, Norway.
  • Raychaudhuri S; Arthritis Research UK Centre for Adolescent Rheumatology, UCL GOS Institute of Child Health, University College London, London, UK.
  • Thompson SD; NIHR-Great Ormond Street Hospital Biomedical Research Centre, London, UK.
  • Thomson W; Arthritis Research UK Centre for Genetics and Genomics, Manchester Academic Health Science Centre, University Of Manchester, Manchester, UK.
Ann Rheum Dis ; 76(4): 765-772, 2017 04.
Article em En | MEDLINE | ID: mdl-27998952
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Artrite Juvenil / Artrite Reumatoide / Fator Reumatoide / Cadeias HLA-DRB1 / Antígenos HLA / Complexo Principal de Histocompatibilidade Tipo de estudo: Observational_studies / Prognostic_studies / Risk_factors_studies Limite: Adult / Child / Humans Idioma: En Revista: Ann Rheum Dis Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Reino Unido
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Artrite Juvenil / Artrite Reumatoide / Fator Reumatoide / Cadeias HLA-DRB1 / Antígenos HLA / Complexo Principal de Histocompatibilidade Tipo de estudo: Observational_studies / Prognostic_studies / Risk_factors_studies Limite: Adult / Child / Humans Idioma: En Revista: Ann Rheum Dis Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Reino Unido