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A New RNA-Based Adjuvant Enhances Virus-Specific Vaccine Responses by Locally Triggering TLR- and RLH-Dependent Effects.
Ziegler, Annett; Soldner, Claudia; Lienenklaus, Stefan; Spanier, Julia; Trittel, Stephanie; Riese, Peggy; Kramps, Thomas; Weiss, Siegfried; Heidenreich, Regina; Jasny, Edith; Guzmán, Carlos A; Kallen, Karl-Josef; Fotin-Mleczek, Mariola; Kalinke, Ulrich.
Afiliação
  • Ziegler A; Institute for Experimental Infection Research, TWINCORE, Centre for Experimental and Clinical Infection Research, a Joint Venture between the Hannover Medical School and the Helmholtz Centre for Infection Research, D-30625 Hannover, Germany.
  • Soldner C; Institute for Experimental Infection Research, TWINCORE, Centre for Experimental and Clinical Infection Research, a Joint Venture between the Hannover Medical School and the Helmholtz Centre for Infection Research, D-30625 Hannover, Germany.
  • Lienenklaus S; Institute for Experimental Infection Research, TWINCORE, Centre for Experimental and Clinical Infection Research, a Joint Venture between the Hannover Medical School and the Helmholtz Centre for Infection Research, D-30625 Hannover, Germany.
  • Spanier J; Department of Molecular Immunology, Helmholtz Centre for Infection Research, D-38124 Braunschweig, Germany.
  • Trittel S; Institute for Laboratory Animal Science and Central Animal Facility, Hannover Medical School, D-30625 Hannover, Germany.
  • Riese P; Institute for Experimental Infection Research, TWINCORE, Centre for Experimental and Clinical Infection Research, a Joint Venture between the Hannover Medical School and the Helmholtz Centre for Infection Research, D-30625 Hannover, Germany.
  • Kramps T; Department of Vaccinology and Applied Microbiology, Helmholtz Centre for Infection Research, D-38124 Braunschweig, Germany; and.
  • Weiss S; Department of Vaccinology and Applied Microbiology, Helmholtz Centre for Infection Research, D-38124 Braunschweig, Germany; and.
  • Heidenreich R; CureVac AG, D-72076 Tübingen, Germany.
  • Jasny E; Department of Molecular Immunology, Helmholtz Centre for Infection Research, D-38124 Braunschweig, Germany.
  • Guzmán CA; CureVac AG, D-72076 Tübingen, Germany.
  • Kallen KJ; CureVac AG, D-72076 Tübingen, Germany.
  • Fotin-Mleczek M; Department of Vaccinology and Applied Microbiology, Helmholtz Centre for Infection Research, D-38124 Braunschweig, Germany; and.
  • Kalinke U; CureVac AG, D-72076 Tübingen, Germany.
J Immunol ; 198(4): 1595-1605, 2017 02 15.
Article em En | MEDLINE | ID: mdl-28077601

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Imunoglobulina G / Glicoproteínas de Membrana / Vacinas contra Influenza / Adjuvantes Imunológicos / RNA não Traduzido / Receptor 7 Toll-Like / Vacinas de Partículas Semelhantes a Vírus Limite: Animals Idioma: En Revista: J Immunol Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Alemanha

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Imunoglobulina G / Glicoproteínas de Membrana / Vacinas contra Influenza / Adjuvantes Imunológicos / RNA não Traduzido / Receptor 7 Toll-Like / Vacinas de Partículas Semelhantes a Vírus Limite: Animals Idioma: En Revista: J Immunol Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Alemanha