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Improved Lysosomal Trafficking Can Modulate the Potency of Antibody Drug Conjugates.
DeVay, Rachel M; Delaria, Kathy; Zhu, Guoyun; Holz, Charles; Foletti, Davide; Sutton, Janette; Bolton, Gary; Dushin, Russell; Bee, Christine; Pons, Jaume; Rajpal, Arvind; Liang, Hong; Shelton, David; Liu, Shu-Hui; Strop, Pavel.
Afiliação
  • DeVay RM; Rinat Laboratories, Pfizer Inc. , 230 East Grand Avenue, South San Francisco, California 94080, United States.
  • Delaria K; Rinat Laboratories, Pfizer Inc. , 230 East Grand Avenue, South San Francisco, California 94080, United States.
  • Zhu G; Rinat Laboratories, Pfizer Inc. , 230 East Grand Avenue, South San Francisco, California 94080, United States.
  • Holz C; Rinat Laboratories, Pfizer Inc. , 230 East Grand Avenue, South San Francisco, California 94080, United States.
  • Foletti D; Rinat Laboratories, Pfizer Inc. , 230 East Grand Avenue, South San Francisco, California 94080, United States.
  • Sutton J; Rinat Laboratories, Pfizer Inc. , 230 East Grand Avenue, South San Francisco, California 94080, United States.
  • Bolton G; Rinat Laboratories, Pfizer Inc. , 230 East Grand Avenue, South San Francisco, California 94080, United States.
  • Dushin R; Worldwide Medicinal Chemistry, Pfizer Inc. , 445 Eastern Point Road, Groton, Connecticut 06340, United States.
  • Bee C; Rinat Laboratories, Pfizer Inc. , 230 East Grand Avenue, South San Francisco, California 94080, United States.
  • Pons J; Rinat Laboratories, Pfizer Inc. , 230 East Grand Avenue, South San Francisco, California 94080, United States.
  • Rajpal A; Rinat Laboratories, Pfizer Inc. , 230 East Grand Avenue, South San Francisco, California 94080, United States.
  • Liang H; Rinat Laboratories, Pfizer Inc. , 230 East Grand Avenue, South San Francisco, California 94080, United States.
  • Shelton D; Rinat Laboratories, Pfizer Inc. , 230 East Grand Avenue, South San Francisco, California 94080, United States.
  • Liu SH; Rinat Laboratories, Pfizer Inc. , 230 East Grand Avenue, South San Francisco, California 94080, United States.
  • Strop P; Rinat Laboratories, Pfizer Inc. , 230 East Grand Avenue, South San Francisco, California 94080, United States.
Bioconjug Chem ; 28(4): 1102-1114, 2017 04 19.
Article em En | MEDLINE | ID: mdl-28151644
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Sistemas de Liberação de Medicamentos / Imunoconjugados / Transcitose / Lisossomos Limite: Animals / Humans Idioma: En Revista: Bioconjug Chem Assunto da revista: BIOQUIMICA Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Estados Unidos
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Sistemas de Liberação de Medicamentos / Imunoconjugados / Transcitose / Lisossomos Limite: Animals / Humans Idioma: En Revista: Bioconjug Chem Assunto da revista: BIOQUIMICA Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Estados Unidos