The elevated activation of NF&#954;B and AP-1 is correlated with differential regulation of Bcl-2 and associated with oral squamous cell carcinoma progression and resistance.

Alam, Manzar; Kashyap, Tanushree; Pramanik, Kamdeo K; Singh, Abhay K; Nagini, Siddavaram; Mishra, Rajakishore

The elevated activation of NFκB and AP-1 is correlated with differential regulation of Bcl-2 and associated with oral squamous cell carcinoma progression and resistance.

Alam, Manzar; Kashyap, Tanushree; Pramanik, Kamdeo K; Singh, Abhay K; Nagini, Siddavaram; Mishra, Rajakishore.

Afiliação

Alam M; Centre for Life Sciences, School of Natural Sciences, Central University of Jharkhand, Ratu-Lohardaga Road, Brambe Ranchi, Jharkhand, 835205, India.
Kashyap T; Centre for Life Sciences, School of Natural Sciences, Central University of Jharkhand, Ratu-Lohardaga Road, Brambe Ranchi, Jharkhand, 835205, India.
Pramanik KK; Centre for Life Sciences, School of Natural Sciences, Central University of Jharkhand, Ratu-Lohardaga Road, Brambe Ranchi, Jharkhand, 835205, India.
Singh AK; Centre for Life Sciences, School of Natural Sciences, Central University of Jharkhand, Ratu-Lohardaga Road, Brambe Ranchi, Jharkhand, 835205, India.
Nagini S; Department of Biochemistry and Biotechnology, Faculty of Science, Annamalai University, Annamalainagar, Tamil Nadu, 608 002, India.
Mishra R; Centre for Life Sciences, School of Natural Sciences, Central University of Jharkhand, Ratu-Lohardaga Road, Brambe Ranchi, Jharkhand, 835205, India. rajakishore.mishra@cuj.ac.in.

Clin Oral Investig ; 21(9): 2721-2731, 2017 Dec.

Article em En | MEDLINE | ID: mdl-28233171

Assuntos

Carcinoma de Células Escamosas/metabolismo; Carcinoma de Células Escamosas/patologia; Neoplasias Bucais/metabolismo; Neoplasias Bucais/patologia; NF-kappa B/metabolismo; Proteínas Proto-Oncogênicas c-bcl-2/metabolismo; Neoplasias da Língua/metabolismo; Neoplasias da Língua/patologia; Fator de Transcrição AP-1/metabolismo; Adulto; Idoso; Biomarcadores Tumorais/metabolismo; Western Blotting; Carcinoma de Células Escamosas/terapia; Quimiorradioterapia; Imunoprecipitação da Cromatina; Progressão da Doença; Feminino; Humanos; Imuno-Histoquímica; Técnicas In Vitro; Masculino; Pessoa de Meia-Idade; Neoplasias Bucais/terapia; Reação em Cadeia da Polimerase em Tempo Real; Neoplasias da Língua/terapia; Regulação para Cima

Palavras-chave

AP-1; Bcl-2; Drug resistance; GSK3α; GSK3ß; NFκB; OSCC; Oral cancer; Oral squamous cell carcinoma; Oral tumor resistance to chemoradiation therapy

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias Bucais / Neoplasias da Língua / Carcinoma de Células Escamosas / NF-kappa B / Fator de Transcrição AP-1 / Proteínas Proto-Oncogênicas c-bcl-2 Tipo de estudo: Risk_factors_studies Limite: Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Revista: Clin Oral Investig Assunto da revista: ODONTOLOGIA Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Índia

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google