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Maternal phthalate exposure promotes allergic airway inflammation over 2 generations through epigenetic modifications.
Jahreis, Susanne; Trump, Saskia; Bauer, Mario; Bauer, Tobias; Thürmann, Loreen; Feltens, Ralph; Wang, Qi; Gu, Lei; Grützmann, Konrad; Röder, Stefan; Averbeck, Marco; Weichenhan, Dieter; Plass, Christoph; Sack, Ulrich; Borte, Michael; Dubourg, Virginie; Schüürmann, Gerrit; Simon, Jan C; von Bergen, Martin; Hackermüller, Jörg; Eils, Roland; Lehmann, Irina; Polte, Tobias.
Afiliação
  • Jahreis S; Department of Environmental Immunology, UFZ-Helmholtz Centre for Environmental Research Leipzig-Halle, Leipzig, Germany; Department of Dermatology, Venerology and Allergology, Leipzig University Medical Center, Leipzig, Germany; Infections in Hematology/Oncology, Leibniz Institute for Natural Produc
  • Trump S; Department of Environmental Immunology, UFZ-Helmholtz Centre for Environmental Research Leipzig-Halle, Leipzig, Germany; Institute of Pharmacy and Molecular Biotechnology, and Bioquant Center, University of Heidelberg, Heidelberg, Germany.
  • Bauer M; Department of Environmental Immunology, UFZ-Helmholtz Centre for Environmental Research Leipzig-Halle, Leipzig, Germany.
  • Bauer T; Division of Theoretical Bioinformatics, German Cancer Research Center (DKFZ), Heidelberg, Germany.
  • Thürmann L; Department of Environmental Immunology, UFZ-Helmholtz Centre for Environmental Research Leipzig-Halle, Leipzig, Germany.
  • Feltens R; Department Molecular Systems Biology, UFZ-Helmholtz Centre for Environmental Research Leipzig-Halle, Leipzig, Germany.
  • Wang Q; Division of Theoretical Bioinformatics, German Cancer Research Center (DKFZ), Heidelberg, Germany.
  • Gu L; Division of Theoretical Bioinformatics, German Cancer Research Center (DKFZ), Heidelberg, Germany; Department of Cell Biology, Harvard Medical School, Boston.
  • Grützmann K; Department of Environmental Immunology, UFZ-Helmholtz Centre for Environmental Research Leipzig-Halle, Leipzig, Germany.
  • Röder S; Department of Environmental Immunology, UFZ-Helmholtz Centre for Environmental Research Leipzig-Halle, Leipzig, Germany.
  • Averbeck M; Department of Dermatology, Venerology and Allergology, Leipzig University Medical Center, Leipzig, Germany.
  • Weichenhan D; Division of Epigenomics and Cancer Risk Factors, German Cancer Research Center (DKFZ), Heidelberg, Germany.
  • Plass C; Division of Epigenomics and Cancer Risk Factors, German Cancer Research Center (DKFZ), Heidelberg, Germany.
  • Sack U; Institute of Clinical Immunology, Medical Faculty, University of Leipzig, Leipzig, Germany.
  • Borte M; Municipal Hospital "St Georg" Children's Hospital, Leipzig, Germany.
  • Dubourg V; Young Investigators Group Bioinformatics and Transcriptomics, Department Molecular Systems Biology, UFZ-Helmholtz Centre for Environmental Research Leipzig-Halle, Leipzig, Germany.
  • Schüürmann G; Department of Ecological Chemistry, UFZ-Helmholtz Centre for Environmental Research Leipzig-Halle, Leipzig, Germany; Institute for Organic Chemistry, Technical University Bergakademie Freiberg, Freiberg, Germany.
  • Simon JC; Department of Dermatology, Venerology and Allergology, Leipzig University Medical Center, Leipzig, Germany.
  • von Bergen M; Department Molecular Systems Biology, UFZ-Helmholtz Centre for Environmental Research Leipzig-Halle, Leipzig, Germany; Institute of Biochemistry, Faculty of Bioscience, Pharmacy and Psychology, University of Leipzig, Leipzig, Germany; Department of Chemistry and Bioscience, University of Aalborg, Aa
  • Hackermüller J; Young Investigators Group Bioinformatics and Transcriptomics, Department Molecular Systems Biology, UFZ-Helmholtz Centre for Environmental Research Leipzig-Halle, Leipzig, Germany.
  • Eils R; Division of Theoretical Bioinformatics, German Cancer Research Center (DKFZ), Heidelberg, Germany; Institute of Pharmacy and Molecular Biotechnology, and Bioquant Center, University of Heidelberg, Heidelberg, Germany; Translational Lung Research Center Heidelberg (TLRC), German Center for Lung Resea
  • Lehmann I; Department of Environmental Immunology, UFZ-Helmholtz Centre for Environmental Research Leipzig-Halle, Leipzig, Germany.
  • Polte T; Department of Environmental Immunology, UFZ-Helmholtz Centre for Environmental Research Leipzig-Halle, Leipzig, Germany; Department of Dermatology, Venerology and Allergology, Leipzig University Medical Center, Leipzig, Germany. Electronic address: tobias.polte@ufz.de.
J Allergy Clin Immunol ; 141(2): 741-753, 2018 02.
Article em En | MEDLINE | ID: mdl-28392331
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Ácidos Ftálicos / Asma / Células Th2 / Exposição Materna / Epigênese Genética Tipo de estudo: Observational_studies / Prognostic_studies / Risk_factors_studies Limite: Adult / Animals / Child / Female / Humans / Newborn / Pregnancy País/Região como assunto: Europa Idioma: En Revista: J Allergy Clin Immunol Ano de publicação: 2018 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Ácidos Ftálicos / Asma / Células Th2 / Exposição Materna / Epigênese Genética Tipo de estudo: Observational_studies / Prognostic_studies / Risk_factors_studies Limite: Adult / Animals / Child / Female / Humans / Newborn / Pregnancy País/Região como assunto: Europa Idioma: En Revista: J Allergy Clin Immunol Ano de publicação: 2018 Tipo de documento: Article