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Exploration of flexible phenylpropylurea scaffold as novel cardiac myosin activators for the treatment of systolic heart failure.
Manickam, Manoj; Jalani, Hitesh B; Pillaiyar, Thanigaimalai; Sharma, Niti; Boggu, Pulla Reddy; Venkateswararao, Eeda; Lee, You-Jung; Jeon, Eun-Seok; Jung, Sang-Hun.
Afiliação
  • Manickam M; College of Pharmacy, Institute of Drug Research and Development, Chungnam National University, Daejeon 34134, South Korea.
  • Jalani HB; College of Pharmacy, Institute of Drug Research and Development, Chungnam National University, Daejeon 34134, South Korea.
  • Pillaiyar T; College of Pharmacy, Institute of Drug Research and Development, Chungnam National University, Daejeon 34134, South Korea.
  • Sharma N; College of Pharmacy, Institute of Drug Research and Development, Chungnam National University, Daejeon 34134, South Korea.
  • Boggu PR; College of Pharmacy, Institute of Drug Research and Development, Chungnam National University, Daejeon 34134, South Korea.
  • Venkateswararao E; College of Pharmacy, Institute of Drug Research and Development, Chungnam National University, Daejeon 34134, South Korea.
  • Lee YJ; Division of Cardiology, Samsung Medical Center, Samsung Biomedical Research Institute, School of Medicine, Sungkyunkwan University, 81 Irwon-Ro, Gangnam-gu, Seoul 06351, South Korea.
  • Jeon ES; Division of Cardiology, Samsung Medical Center, Samsung Biomedical Research Institute, School of Medicine, Sungkyunkwan University, 81 Irwon-Ro, Gangnam-gu, Seoul 06351, South Korea.
  • Jung SH; College of Pharmacy, Institute of Drug Research and Development, Chungnam National University, Daejeon 34134, South Korea. Electronic address: jungshh@cnu.ac.kr.
Eur J Med Chem ; 134: 379-391, 2017 Jul 07.
Article em En | MEDLINE | ID: mdl-28432943
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Ureia / Cardiotônicos / Miosinas Cardíacas / Insuficiência Cardíaca Sistólica / Coração Limite: Animals / Humans / Male Idioma: En Revista: Eur J Med Chem Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Coréia do Sul
Texto completo
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XML
PubMed Links
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Ureia / Cardiotônicos / Miosinas Cardíacas / Insuficiência Cardíaca Sistólica / Coração Limite: Animals / Humans / Male Idioma: En Revista: Eur J Med Chem Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Coréia do Sul