A novel mass spectrometry-based method for simultaneous determination of asymmetric and symmetric dimethylarginine, l-arginine and l-citrulline optimized for LC-MS-TOF and LC-MS/MS.

Wisniewski, Jerzy; Fleszar, Mariusz G; Piechowicz, Joanna; Krzystek-Korpacka, Malgorzata; Chachaj, Angelika; Szuba, Andrzej; Lorenc-Kukula, Katarzyna; Maslowski, Leszek; Witkiewicz, Wojciech; Gamian, Andrzej

Wisniewski, Jerzy; Fleszar, Mariusz G; Piechowicz, Joanna; Krzystek-Korpacka, Malgorzata; Chachaj, Angelika; Szuba, Andrzej; Lorenc-Kukula, Katarzyna; Maslowski, Leszek; Witkiewicz, Wojciech; Gamian, Andrzej.

Afiliação

Wisniewski J; Department of Medical Biochemistry, Wroclaw Medical University, Wroclaw, Poland.
Fleszar MG; Department of Medical Biochemistry, Wroclaw Medical University, Wroclaw, Poland.
Piechowicz J; Department of Medical Biochemistry, Wroclaw Medical University, Wroclaw, Poland.
Krzystek-Korpacka M; Department of Medical Biochemistry, Wroclaw Medical University, Wroclaw, Poland.
Chachaj A; Department of Angiology, Wroclaw Medical University, Wroclaw, Poland.
Szuba A; Department of Internal Medicine, 4th Military Hospital, Wroclaw, Poland.
Lorenc-Kukula K; Department of Angiology, Wroclaw Medical University, Wroclaw, Poland.
Maslowski L; Department of Internal Medicine, 4th Military Hospital, Wroclaw, Poland.
Witkiewicz W; Shimadzu Center For Advanced Analytical Chemistry, The University of Texas at Arlington, TX, USA.
Gamian A; Department of Vascular Surgery, Regional Specialist Hospital, Wroclaw, Poland.

Biomed Chromatogr ; 31(11)2017 Nov.

Article em En | MEDLINE | ID: mdl-28436051

Assuntos

Arginina/análogos & derivados; Arginina/sangue; Citrulina/sangue; Arginina/química; Arginina/metabolismo; Cromatografia Líquida/métodos; Citrulina/química; Citrulina/metabolismo; Humanos; Limite de Detecção; Modelos Lineares; Óxido Nítrico/metabolismo; Reprodutibilidade dos Testes; Espectrometria de Massas em Tandem/métodos

Palavras-chave

ADMA; amino acids derivatization; electrospray ionization; liquid chromatography-mass spectrometry; nitric oxide; quantitative analysis

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Arginina / Citrulina Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Revista: Biomed Chromatogr Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Polônia

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