Krüppel-like factor 17 inhibits urokinase plasminogen activator gene expression to suppress cell invasion through the Src/p38/ MAPK signaling pathway in human lung adenocarcionma.

Cai, Xing-Dong; Che, Li; Lin, Jia-Xin; Huang, Shuai; Li, Jiong; Liu, Xiao-Yan; Pan, Xing-Fei; Wang, Qin-Qin; Chen, Li; Lin, Ming-Juan; Huang, Zhi-Hong; Ma, Hong-Ming; Wu, Yi; Liu, Sheng-Ming; Zhou, Yan-Bin

Cai, Xing-Dong; Che, Li; Lin, Jia-Xin; Huang, Shuai; Li, Jiong; Liu, Xiao-Yan; Pan, Xing-Fei; Wang, Qin-Qin; Chen, Li; Lin, Ming-Juan; Huang, Zhi-Hong; Ma, Hong-Ming; Wu, Yi; Liu, Sheng-Ming; Zhou, Yan-Bin.

Afiliação

Cai XD; Department of Respiratory, The First Affiliated Hospital of Jinan University, Guangzhou 510630, China.
Che L; Department of Respiratory, The First Affiliated Hospital of Jinan University, Guangzhou 510630, China.
Lin JX; Department of Respiratory, The First Affiliated Hospital of Jinan University, Guangzhou 510630, China.
Huang S; Department of Orthopedics, The Second Affiliated Hospital of Guangzhou Medical University, Guangzhou 510260, China.
Li J; Department of Anatomy, The Medical College of Jinan University, Guangzhou 510630, China.
Liu XY; Department of Respiratory, The First Affiliated Hospital of Jinan University, Guangzhou 510630, China.
Pan XF; Department of Infectious Disease, The Third Affiliated Hospital of Guangzhou Medical University, Guangzhou 510150, China.
Wang QQ; Department of Respiratory, The First Affiliated Hospital of Jinan University, Guangzhou 510630, China.
Chen L; Department of Respiratory, The First Affiliated Hospital of Jinan University, Guangzhou 510630, China.
Lin MJ; Department of Respiratory, The First Affiliated Hospital of Jinan University, Guangzhou 510630, China.
Huang ZH; Department of Respiratory, The First Affiliated Hospital of Jinan University, Guangzhou 510630, China.
Ma HM; Department of Respiratory, The First Affiliated Hospital of Jinan University, Guangzhou 510630, China.
Wu Y; Department of Respiratory, The First Affiliated Hospital of Jinan University, Guangzhou 510630, China.
Liu SM; Department of Respiratory, The First Affiliated Hospital of Jinan University, Guangzhou 510630, China.
Zhou YB; Department of Pulmonary Medicine, The First Affiliated Hospital of Sun Yat-Sen University, Guangzhou 510080, China.

Oncotarget ; 8(24): 38743-38754, 2017 Jun 13.

Article em En | MEDLINE | ID: mdl-28454121

Assuntos

Adenocarcinoma/secundário; Movimento Celular; Neoplasias Pulmonares/patologia; Proteínas de Membrana/metabolismo; Proteínas Proto-Oncogênicas pp60(c-src)/metabolismo; Fatores de Transcrição/metabolismo; Proteínas Quinases p38 Ativadas por Mitógeno/metabolismo; Adenocarcinoma/genética; Adenocarcinoma/metabolismo; Apoptose; Biomarcadores Tumorais/genética; Biomarcadores Tumorais/metabolismo; Proliferação de Células; Humanos; Neoplasias Pulmonares/genética; Neoplasias Pulmonares/metabolismo; Metástase Linfática; Proteínas de Membrana/genética; Invasividade Neoplásica; Prognóstico; Proteínas Proto-Oncogênicas pp60(c-src)/genética; Taxa de Sobrevida; Fatores de Transcrição/genética; Células Tumorais Cultivadas; Proteínas Quinases p38 Ativadas por Mitógeno/genética

Palavras-chave

Krüppel-like-factor 17(KLF17); invasion; lung adenocarcinoma; signal pathway; urokinase plasminogen activator (uPA)

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Fatores de Transcrição / Adenocarcinoma / Movimento Celular / Proteínas Proto-Oncogênicas pp60(c-src) / Proteínas Quinases p38 Ativadas por Mitógeno / Neoplasias Pulmonares / Proteínas de Membrana Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Revista: Oncotarget Ano de publicação: 2017 Tipo de documento: Article País de afiliação: China

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