Adipocyte-myofibroblast transition as a possible pathophysiological step in androgenetic alopecia.
Exp Dermatol
; 26(6): 522-523, 2017 06.
Article
em En
| MEDLINE
| ID: mdl-28482134
ABSTRACT
Appearance of local fibrotic structures around and beneath hair follicles during their involution is a known hallmark of androgenetic alopecia (AGA). We hypothesise that this fibrosis can be connected with recently uncovered adipocyte-myofibroblast transition (AMT) involving the dermal adipocytes. This reflects that AMT is at least partially androgen-dependent, and we propose that AMT may play a role in AGA.
Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Adipócitos
/
Folículo Piloso
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Alopecia
/
Miofibroblastos
Limite:
Animals
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Female
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Humans
/
Male
Idioma:
En
Revista:
Exp Dermatol
Assunto da revista:
DERMATOLOGIA
Ano de publicação:
2017
Tipo de documento:
Article
País de afiliação:
Alemanha