Positive Modulatory Interactions of NMDA Receptor GluN1/2B Ligand Binding Domains Attenuate Antagonists Activity.

Bledsoe, Douglas; Tamer, Ceyhun; Mesic, Ivana; Madry, Christian; Klein, Bradley G; Laube, Bodo; Costa, Blaise M

Bledsoe, Douglas; Tamer, Ceyhun; Mesic, Ivana; Madry, Christian; Klein, Bradley G; Laube, Bodo; Costa, Blaise M.

Afiliação

Bledsoe D; Edward Via College of Osteopathic MedicineBlacksburg, VA, USA.
Tamer C; Department of Neurophysiology and Neurosensory Systems, Technische Universität DarmstadtDarmstadt, Germany.
Mesic I; Department of Neurophysiology and Neurosensory Systems, Technische Universität DarmstadtDarmstadt, Germany.
Madry C; Department of Neuroscience, Physiology and Pharmacology, University College LondonLondon, UK.
Klein BG; Department of Biomedical Sciences & Pathobiology, Virginia-Maryland College of Veterinary Medicine, Virginia TechBlacksburg, VA, USA.
Laube B; Department of Neurophysiology and Neurosensory Systems, Technische Universität DarmstadtDarmstadt, Germany.
Costa BM; Edward Via College of Osteopathic MedicineBlacksburg, VA, USA.

Front Pharmacol ; 8: 229, 2017.

Article em En | MEDLINE | ID: mdl-28536523

Palavras-chave

Ligand Binding Domain (LBD); NMDA receptor; competitive antagonists; interface; memantine

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Revista: Front Pharmacol Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Estados Unidos

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