Neighbourhood deprivation is positively associated with detection of the ultra-high risk (UHR) state for psychosis in South East London.
Schizophr Res
; 192: 371-376, 2018 02.
Article
em En
| MEDLINE
| ID: mdl-28601502
ABSTRACT
BACKGROUND:
Individuals are defined as being at ultra-high risk (UHR) for psychosis based on a combination of attenuated psychotic symptoms, help-seeking behaviour, genetic risk, and social/occupational deterioration. Limited evidence is available on whether UHR detection differs by neighbourhood, and potential explanations.AIMS:
To examine neighbourhood distribution of detected UHR using cases from the OASIS service in South East London, investigating neighbourhood deprivation as an explanatory variable.METHODS:
Geographic data were collected on patients who met UHR criteria over a fourteen-year period, at the neighbourhood (lower super output area, LSOA) level. Rates were calculated based on cases and age-specific population estimates. Poisson regression assessed associations between UHR rate and neighbourhood deprivation, and with particular deprivation domains, adjusting for referrals for UHR assessment, population density, and proportions of non-White people, and young single people.RESULTS:
Rate of UHR detection was statistically related to neighbourhood deprivation, but referral rate was not compared to the least deprived neighbourhoods, the most deprived neighbourhoods had a greater than two-fold increase in incidence rate of detected UHR (adjusted incidence rate ratio (IRR) 2.11, 95% confidence interval (CI) 1.21,3.67). In contrast, a small, imprecise association was observed for referral for assessment for UHR (adjusted IRR 1.26 (95%CI 0.84,1.89)). Evidence was also found for associations of UHR detection rate with domains of deprivation pertaining to health and barriers to services.CONCLUSIONS:
The distribution of UHR detection rates by neighbourhood is not random and may be explained in part by differences in the social environment between neighbourhoods.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Carência Psicossocial
/
Transtornos Psicóticos
/
Características de Residência
/
Sintomas Prodrômicos
Tipo de estudo:
Diagnostic_studies
/
Etiology_studies
/
Observational_studies
/
Risk_factors_studies
Limite:
Female
/
Humans
/
Male
País/Região como assunto:
Europa
Idioma:
En
Revista:
Schizophr Res
Assunto da revista:
PSIQUIATRIA
Ano de publicação:
2018
Tipo de documento:
Article