Modified Technique of Cultured Epithelial Cells Transplantation on Facial Segmental Vitiligo.
J Craniofac Surg
; 28(6): 1462-1467, 2017 Sep.
Article
em En
| MEDLINE
| ID: mdl-28708646
ABSTRACT
BACKGROUND:
Cultured epithelial cells transplantation is a known surgical technique for vitiligo.OBJECTIVE:
To evaluate the factors influencing efficacy and safety of cultured epithelial cells transplantation in 9-month follow-up.METHODS:
Demographic, clinical, and repigmentation outcomes were reviewed for patients with facial segmental vitiligo who had undergone cultured epithelial cells transplantation from November 2013 to July 2015 at the clinic of the Department of Dermatology, Huashan Hospital, China.RESULTS:
Twenty-eight patients who had undergone cultured epithelial cells transplantation were included. A satisfactory result (>50% repigmentation) was achieved in 79% patients with facial segmental vitiligo in 9 months. The treatment effect was significantly different in 6th month (Pâ=â0.032), 9th month (Pâ=â0.006) compared with 3rd month. Disease stability did significantly affect repigmentation outcome in 9th month (Zâ=â2.113, Pâ=â0.035). No significant difference was observed between single segmental type versus mixed type (Zâ=â1.081, Pâ=â0.280). Adverse effects were nearly absent.CONCLUSION:
Cultured epithelial cells transplantation is a relatively safe and effective therapy for facial segmental stable vitiligo patients.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Vitiligo
/
Células Cultivadas
/
Transplante de Células
/
Células Epiteliais
/
Face
Limite:
Humans
Idioma:
En
Revista:
J Craniofac Surg
Assunto da revista:
ODONTOLOGIA
Ano de publicação:
2017
Tipo de documento:
Article
País de afiliação:
China