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S1PR1 on tumor-associated macrophages promotes lymphangiogenesis and metastasis via NLRP3/IL-1ß.
Weichand, Benjamin; Popp, Rüdiger; Dziumbla, Sarah; Mora, Javier; Strack, Elisabeth; Elwakeel, Eiman; Frank, Ann-Christin; Scholich, Klaus; Pierre, Sandra; Syed, Shahzad N; Olesch, Catherine; Ringleb, Julia; Ören, Bilge; Döring, Claudia; Savai, Rajkumar; Jung, Michaela; von Knethen, Andreas; Levkau, Bodo; Fleming, Ingrid; Weigert, Andreas; Brüne, Bernhard.
Afiliação
  • Weichand B; Institute of Biochemistry I, Faculty of Medicine, Goethe-University Frankfurt, Frankfurt, Germany.
  • Popp R; Institute of Vascular Signaling, Faculty of Medicine, Goethe-University Frankfurt, Frankfurt, Germany.
  • Dziumbla S; Institute of Vascular Signaling, Faculty of Medicine, Goethe-University Frankfurt, Frankfurt, Germany.
  • Mora J; Institute of Biochemistry I, Faculty of Medicine, Goethe-University Frankfurt, Frankfurt, Germany.
  • Strack E; Institute of Biochemistry I, Faculty of Medicine, Goethe-University Frankfurt, Frankfurt, Germany.
  • Elwakeel E; Institute of Biochemistry I, Faculty of Medicine, Goethe-University Frankfurt, Frankfurt, Germany.
  • Frank AC; Institute of Biochemistry I, Faculty of Medicine, Goethe-University Frankfurt, Frankfurt, Germany.
  • Scholich K; Institute of Clinical Pharmacology/Center for Drug Research, Development and Safety (ZAFES), Faculty of Medicine, Goethe-University Frankfurt, Frankfurt, Germany.
  • Pierre S; Institute of Clinical Pharmacology/Center for Drug Research, Development and Safety (ZAFES), Faculty of Medicine, Goethe-University Frankfurt, Frankfurt, Germany.
  • Syed SN; Institute of Biochemistry I, Faculty of Medicine, Goethe-University Frankfurt, Frankfurt, Germany.
  • Olesch C; Institute of Biochemistry I, Faculty of Medicine, Goethe-University Frankfurt, Frankfurt, Germany.
  • Ringleb J; Institute of Biochemistry I, Faculty of Medicine, Goethe-University Frankfurt, Frankfurt, Germany.
  • Ören B; Institute of Biochemistry I, Faculty of Medicine, Goethe-University Frankfurt, Frankfurt, Germany.
  • Döring C; Dr. Senckenberg Institute for Pathology, Goethe-University Frankfurt, Frankfurt, Germany.
  • Savai R; Max-Planck-Institute for Heart and Lung Research, Department of Lung Development and Remodeling, German Center for Lung Research (DZL), Bad Nauheim, Germany.
  • Jung M; Institute of Biochemistry I, Faculty of Medicine, Goethe-University Frankfurt, Frankfurt, Germany.
  • von Knethen A; Institute of Biochemistry I, Faculty of Medicine, Goethe-University Frankfurt, Frankfurt, Germany.
  • Levkau B; Institute of Pathophysiology, West German Heart and Vascular Center, University Hospital Essen, University of Duisburg-Essen, Essen, Germany.
  • Fleming I; Institute of Vascular Signaling, Faculty of Medicine, Goethe-University Frankfurt, Frankfurt, Germany.
  • Weigert A; Institute of Biochemistry I, Faculty of Medicine, Goethe-University Frankfurt, Frankfurt, Germany weigert@biochem.uni-frankfurt.de.
  • Brüne B; Institute of Biochemistry I, Faculty of Medicine, Goethe-University Frankfurt, Frankfurt, Germany b.bruene@biochem.uni-frankfurt.de.
J Exp Med ; 214(9): 2695-2713, 2017 Sep 04.
Article em En | MEDLINE | ID: mdl-28739604
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Linfangiogênese / Receptores de Lisoesfingolipídeo / Interleucina-1beta / Proteína 3 que Contém Domínio de Pirina da Família NLR / Macrófagos / Metástase Neoplásica Tipo de estudo: Risk_factors_studies Limite: Animals / Female / Humans Idioma: En Revista: J Exp Med Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Alemanha
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Linfangiogênese / Receptores de Lisoesfingolipídeo / Interleucina-1beta / Proteína 3 que Contém Domínio de Pirina da Família NLR / Macrófagos / Metástase Neoplásica Tipo de estudo: Risk_factors_studies Limite: Animals / Female / Humans Idioma: En Revista: J Exp Med Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Alemanha