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Recombinant human IgG1 based Fc multimers, with limited FcR binding capacity, can effectively inhibit complement-mediated disease.
Sun, Haoping; Olsen, Henrik S; Mérigeon, Emmanuel Y; So, Edward; Burch, Erin; Kinsey, Susan; Papadimitriou, John C; Drachenberg, Cinthia B; Bentzen, Søren M; Block, David S; Strome, Scott E; Zhang, Xiaoyu.
Afiliação
  • Sun H; Department of Otorhinolaryngology-Head and Neck Surgery, University of Maryland School of Medicine, 16 S. Eutaw Street, Baltimore, MD, 21201, USA; Department of Hematology, Chengdu Military General Hospital, Chengdu, China.
  • Olsen HS; Gliknik Inc., Baltimore, MD, 21201, USA.
  • Mérigeon EY; Gliknik Inc., Baltimore, MD, 21201, USA.
  • So E; Department of Otorhinolaryngology-Head and Neck Surgery, University of Maryland School of Medicine, 16 S. Eutaw Street, Baltimore, MD, 21201, USA.
  • Burch E; Department of Otorhinolaryngology-Head and Neck Surgery, University of Maryland School of Medicine, 16 S. Eutaw Street, Baltimore, MD, 21201, USA.
  • Kinsey S; Gliknik Inc., Baltimore, MD, 21201, USA.
  • Papadimitriou JC; Department of Pathology, University of Maryland School of Medicine, Baltimore, MD, USA.
  • Drachenberg CB; Department of Pathology, University of Maryland School of Medicine, Baltimore, MD, USA.
  • Bentzen SM; Department of Epidemiology and Public Health, Division of Biostatistics and Bioinformatics, University of Maryland School of Medicine, Baltimore, MD, USA.
  • Block DS; Gliknik Inc., Baltimore, MD, 21201, USA.
  • Strome SE; Department of Otorhinolaryngology-Head and Neck Surgery, University of Maryland School of Medicine, 16 S. Eutaw Street, Baltimore, MD, 21201, USA. Electronic address: sstrome@som.umaryland.edu.
  • Zhang X; Department of Otorhinolaryngology-Head and Neck Surgery, University of Maryland School of Medicine, 16 S. Eutaw Street, Baltimore, MD, 21201, USA. Electronic address: xyzhang@som.umaryland.edu.
J Autoimmun ; 84: 97-108, 2017 Nov.
Article em En | MEDLINE | ID: mdl-28830653
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proteínas do Sistema Complemento / Imunoglobulina G / Fragmentos Fc das Imunoglobulinas / Complemento C1q / Eritrócitos / Doenças do Sistema Imunitário Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Revista: J Autoimmun Assunto da revista: ALERGIA E IMUNOLOGIA Ano de publicação: 2017 Tipo de documento: Article País de afiliação: China
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proteínas do Sistema Complemento / Imunoglobulina G / Fragmentos Fc das Imunoglobulinas / Complemento C1q / Eritrócitos / Doenças do Sistema Imunitário Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Revista: J Autoimmun Assunto da revista: ALERGIA E IMUNOLOGIA Ano de publicação: 2017 Tipo de documento: Article País de afiliação: China