Age-specific infectious period shapes dynamics of pneumonia in bighorn sheep.
Ecol Lett
; 20(10): 1325-1336, 2017 10.
Article
em En
| MEDLINE
| ID: mdl-28871636
ABSTRACT
Superspreading, the phenomenon where a small proportion of individuals contribute disproportionately to new infections, has profound effects on disease dynamics. Superspreading can arise through variation in contacts, infectiousness or infectious periods. The latter has received little attention, yet it drives the dynamics of many diseases of critical public health, livestock health and conservation concern. Here, we present rare evidence of variation in infectious periods underlying a superspreading phenomenon in a free-ranging wildlife system. We detected persistent infections of Mycoplasma ovipneumoniae, the primary causative agent of pneumonia in bighorn sheep (Ovis canadensis), in a small number of older individuals that were homozygous at an immunologically relevant genetic locus. Interactions among age-structure, genetic composition and infectious periods may drive feedbacks in disease dynamics that determine the magnitude of population response to infection. Accordingly, variation in initial conditions may explain divergent population responses to infection that range from recovery to catastrophic decline and extirpation.
Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Pneumonia por Mycoplasma
/
Doenças dos Ovinos
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Carneiro da Montanha
Limite:
Animals
Idioma:
En
Revista:
Ecol Lett
Ano de publicação:
2017
Tipo de documento:
Article
País de afiliação:
Estados Unidos