SnapShot: Connexins and Disease.

Laird, Dale W; Naus, Christian C; Lampe, Paul D

Laird, Dale W; Naus, Christian C; Lampe, Paul D.

Afiliação

Laird DW; Department of Anatomy and Cell Biology, University of Western Ontario, London, ON N6A 5C1, Canada.
Naus CC; Department of Cellular & Physiological Sciences, University of British Columbia, Vancouver, BC V6T 1Z3, Canada.
Lampe PD; Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA.

Cell ; 170(6): 1260-1260.e1, 2017 Sep 07.

Article em En | MEDLINE | ID: mdl-28886388

ABSTRACT

ABSTRACT

The connexin family of membrane proteins enable gap junction formation and homeostasis, supporting communication between adjacent cells. This SnapShot highlights mutations in different connexins associated with human pathologies and how they affect gap junction function.

Assuntos

Conexinas/metabolismo; Doença/genética; Conexinas/química; Conexinas/genética; Junções Comunicantes; Humanos; Mutação

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Doença / Conexinas Limite: Humans Idioma: En Revista: Cell Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Canadá

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