Cobalamin-Associated Superoxide Scavenging in Neuronal Cells Is a Potential Mechanism for Vitamin B<sub>12</sub>-Deprivation Optic Neuropathy.

Chan, Wesley; Almasieh, Mohammadali; Catrinescu, Maria-Magdalena; Levin, Leonard A

Cobalamin-Associated Superoxide Scavenging in Neuronal Cells Is a Potential Mechanism for Vitamin B₁₂-Deprivation Optic Neuropathy.

Chan, Wesley; Almasieh, Mohammadali; Catrinescu, Maria-Magdalena; Levin, Leonard A.

Afiliação

Chan W; Maisonneuve-Rosemont Hospital Research Center and Department of Ophthalmology, University of Montreal, Montreal, Quebec, Canada.
Almasieh M; Maisonneuve-Rosemont Hospital Research Center and Department of Ophthalmology, University of Montreal, Montreal, Quebec, Canada; Department of Ophthalmology, McGill University, Montreal, Quebec, Canada; Department of Neurology and Neurosurgery, McGill University, Montreal, Quebec, Canada.
Catrinescu MM; Maisonneuve-Rosemont Hospital Research Center and Department of Ophthalmology, University of Montreal, Montreal, Quebec, Canada; Department of Ophthalmology, McGill University, Montreal, Quebec, Canada; Department of Neurology and Neurosurgery, McGill University, Montreal, Quebec, Canada.
Levin LA; Maisonneuve-Rosemont Hospital Research Center and Department of Ophthalmology, University of Montreal, Montreal, Quebec, Canada; Department of Ophthalmology, McGill University, Montreal, Quebec, Canada; Department of Neurology and Neurosurgery, McGill University, Montreal, Quebec, Canada; Department

Am J Pathol ; 188(1): 160-172, 2018 01.

Article em En | MEDLINE | ID: mdl-29037851

Assuntos

Neurônios/metabolismo; Fármacos Neuroprotetores/farmacologia; Doenças do Nervo Óptico/metabolismo; Superóxidos/metabolismo; Deficiência de Vitamina B 12/metabolismo; Vitamina B 12/farmacologia; Animais; Sobrevivência Celular/efeitos dos fármacos; Feminino; Neurônios/efeitos dos fármacos; Ratos; Ratos Long-Evans; Vitamina K 3/farmacologia

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Vitamina B 12 / Deficiência de Vitamina B 12 / Doenças do Nervo Óptico / Superóxidos / Fármacos Neuroprotetores / Neurônios Tipo de estudo: Risk_factors_studies Limite: Animals Idioma: En Revista: Am J Pathol Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Canadá

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