VDR independent induction of acid-sphingomyelinase by 1,23(OH)<sub>2</sub> D<sub>3</sub> in gastric cancer cells: Impact on apoptosis and cell morphology.

Albi, Elisabetta; Cataldi, Samuela; Ferri, Ivana; Sidoni, Angelo; Traina, Giovanna; Fettucciari, Katia; Ambesi-Impiombato, Francesco Saverio; Lazzarini, Andrea; Curcio, Francesco; Ceccarini, Maria Rachele; Beccari, Tommaso; Codini, Michela

VDR independent induction of acid-sphingomyelinase by 1,23(OH)₂ D₃ in gastric cancer cells: Impact on apoptosis and cell morphology.

Albi, Elisabetta; Cataldi, Samuela; Ferri, Ivana; Sidoni, Angelo; Traina, Giovanna; Fettucciari, Katia; Ambesi-Impiombato, Francesco Saverio; Lazzarini, Andrea; Curcio, Francesco; Ceccarini, Maria Rachele; Beccari, Tommaso; Codini, Michela.

Afiliação

Albi E; Department of Pharmaceutical Science, University of Perugia, Italy.
Cataldi S; Department of Pharmaceutical Science, University of Perugia, Italy.
Ferri I; Institute of Pathologic Anatomy and Histology, University of Perugia, Italy.
Sidoni A; Institute of Pathologic Anatomy and Histology, University of Perugia, Italy.
Traina G; Department of Pharmaceutical Science, University of Perugia, Italy.
Fettucciari K; Department of Experimental Medicine, University of Perugia, Italy.
Ambesi-Impiombato FS; Department of Clinical and Biological Sciences, University of Udine, Italy.
Lazzarini A; Laboratory of Nuclear Lipid BioPathology, CRABiON, Perugia, Italy.
Curcio F; Department of Clinical and Biological Sciences, University of Udine, Italy.
Ceccarini MR; Department of Pharmaceutical Science, University of Perugia, Italy.
Beccari T; Department of Pharmaceutical Science, University of Perugia, Italy.
Codini M; Department of Pharmaceutical Science, University of Perugia, Italy. Electronic address: michela.codini@unipg.it.

Biochimie ; 146: 35-42, 2018 Mar.

Article em En | MEDLINE | ID: mdl-29158006

Assuntos

Apoptose/efeitos dos fármacos; Calcitriol/farmacologia; Esfingomielina Fosfodiesterase/biossíntese; Neoplasias Gástricas/patologia; Linhagem Celular Tumoral; Indução Enzimática/efeitos dos fármacos; Humanos; Polimorfismo Genético/efeitos dos fármacos; Receptores de Calcitriol/genética; Receptores de Calcitriol/metabolismo; Receptor 2 de Fatores de Crescimento do Endotélio Vascular/genética

Palavras-chave

Acid sphingomyelinase; Gastric cancer cells; PTEN; Vitamin D; Vitamin D receptor

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Esfingomielina Fosfodiesterase / Neoplasias Gástricas / Calcitriol / Apoptose Limite: Humans Idioma: En Revista: Biochimie Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Itália

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