Phosphate (Pi)-regulated heterodimerization of the high-affinity sodium-dependent Pi transporters PiT1/Slc20a1 and PiT2/Slc20a2 underlies extracellular Pi sensing independently of Pi uptake.

Bon, Nina; Couasnay, Greig; Bourgine, Annabelle; Sourice, Sophie; Beck-Cormier, Sarah; Guicheux, Jérôme; Beck, Laurent

Phosphate (P_i)-regulated heterodimerization of the high-affinity sodium-dependent P_i transporters PiT1/Slc20a1 and PiT2/Slc20a2 underlies extracellular P_i sensing independently of P_i uptake.

Bon, Nina; Couasnay, Greig; Bourgine, Annabelle; Sourice, Sophie; Beck-Cormier, Sarah; Guicheux, Jérôme; Beck, Laurent.

Afiliação

Bon N; From INSERM, U1229, RMeS "Regenerative Medicine and Skeleton," STEP team "Skeletal Physiopathology and Joint Regenerative Medicine," Nantes F-44042, France.
Couasnay G; the Université de Nantes, UMR-S 1229, RMeS, UFR Odontologie, Nantes F-44042, France, and.
Bourgine A; From INSERM, U1229, RMeS "Regenerative Medicine and Skeleton," STEP team "Skeletal Physiopathology and Joint Regenerative Medicine," Nantes F-44042, France.
Sourice S; the Université de Nantes, UMR-S 1229, RMeS, UFR Odontologie, Nantes F-44042, France, and.
Beck-Cormier S; From INSERM, U1229, RMeS "Regenerative Medicine and Skeleton," STEP team "Skeletal Physiopathology and Joint Regenerative Medicine," Nantes F-44042, France.
Guicheux J; the Université de Nantes, UMR-S 1229, RMeS, UFR Odontologie, Nantes F-44042, France, and.
Beck L; From INSERM, U1229, RMeS "Regenerative Medicine and Skeleton," STEP team "Skeletal Physiopathology and Joint Regenerative Medicine," Nantes F-44042, France.

J Biol Chem ; 293(6): 2102-2114, 2018 02 09.

Article em En | MEDLINE | ID: mdl-29233890

Assuntos

Fosfatos/metabolismo; Multimerização Proteica; Proteínas Cotransportadoras de Sódio-Fosfato Tipo III/metabolismo; Animais; Transporte Biológico; Sistema de Sinalização das MAP Quinases; Mamíferos; Fosfatos/fisiologia; Fosforilação; Ligação Proteica; Transdução de Sinais

Palavras-chave

PiT1; PiT2; bioluminescence resonance energy transfer (BRET); bone; cartilage; extracellular-signal-regulated kinase (ERK); membrane transporters; phosphate sensing; signaling

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Fosfatos / Proteínas Cotransportadoras de Sódio-Fosfato Tipo III / Multimerização Proteica Limite: Animals Idioma: En Revista: J Biol Chem Ano de publicação: 2018 Tipo de documento: Article País de afiliação: França

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google