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The GluN2B subunit represents a major functional determinant of NMDA receptors in human induced pluripotent stem cell-derived cortical neurons.
Neagoe, Ioana; Liu, Chang; Stumpf, Alexander; Lu, Yanmei; He, Dongping; Francis, Ross; Chen, Jun; Reynen, Paul; Alaoui-Ismaili, Moulay Hicham; Fukui, Hirokazu.
Afiliação
  • Neagoe I; Evotec AG, Essener Bogen 7, 22419 Hamburg, Germany.
  • Liu C; Department of Biochemical and Cellular Pharmacology, Genentech, 1 DNA Way, South San Francisco, CA 94080, USA.
  • Stumpf A; Institute for Neurophysiology, Goethe University, Theodor-Stern-Kai 7, Frankfurt 60590, Germany.
  • Lu Y; Department of Biochemical and Cellular Pharmacology, Genentech, 1 DNA Way, South San Francisco, CA 94080, USA.
  • He D; Department of Biochemical and Cellular Pharmacology, Genentech, 1 DNA Way, South San Francisco, CA 94080, USA.
  • Francis R; Department of Biochemical and Cellular Pharmacology, Genentech, 1 DNA Way, South San Francisco, CA 94080, USA.
  • Chen J; Department of Biochemical and Cellular Pharmacology, Genentech, 1 DNA Way, South San Francisco, CA 94080, USA.
  • Reynen P; Department of Biochemical and Cellular Pharmacology, Genentech, 1 DNA Way, South San Francisco, CA 94080, USA.
  • Alaoui-Ismaili MH; Department of Biochemical and Cellular Pharmacology, Genentech, 1 DNA Way, South San Francisco, CA 94080, USA. Electronic address: hicham@symic.bio.
  • Fukui H; Evotec AG, Essener Bogen 7, 22419 Hamburg, Germany. Electronic address: hirokazu.fukui@evotec.com.
Stem Cell Res ; 28: 105-114, 2018 04.
Article em En | MEDLINE | ID: mdl-29454156
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Córtex Cerebral / Receptores de N-Metil-D-Aspartato / Subunidades Proteicas / Células-Tronco Pluripotentes Induzidas / Neurônios Limite: Animals / Humans Idioma: En Revista: Stem Cell Res Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Alemanha
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Córtex Cerebral / Receptores de N-Metil-D-Aspartato / Subunidades Proteicas / Células-Tronco Pluripotentes Induzidas / Neurônios Limite: Animals / Humans Idioma: En Revista: Stem Cell Res Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Alemanha