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When monoclonal antibodies are not monospecific: Hybridomas frequently express additional functional variable regions.
Bradbury, Andrew R M; Trinklein, Nathan D; Thie, Holger; Wilkinson, Ian C; Tandon, Atul K; Anderson, Stephen; Bladen, Catherine L; Jones, Brittany; Aldred, Shelley Force; Bestagno, Marco; Burrone, Oscar; Maynard, Jennifer; Ferrara, Fortunato; Trimmer, James S; Görnemann, Janina; Glanville, Jacob; Wolf, Philipp; Frenzel, Andre; Wong, Julin; Koh, Xin Yu; Eng, Hui-Yan; Lane, David; Lefranc, Marie-Paule; Clark, Mike; Dübel, Stefan.
Afiliação
  • Bradbury ARM; a Specifica Inc. , 1512 Pacheco St, Santa Fe , NM , USA.
  • Trinklein ND; b SwitchGear Genomics , 1914 Palomar Oaks Way, Carlsbad , CA USA.
  • Thie H; c Miltenyi Biotec GmbH , Friedrich-Ebert-Str. 68, Bergisch Gladbach , Germany.
  • Wilkinson IC; d Absolute Antibody, Wilton Centre , Redcar , Cleveland TS10 4RF , United Kingdom.
  • Tandon AK; e NeoBiotechnologies , 2 Union Square, Union City , CA , USA.
  • Anderson S; d Absolute Antibody, Wilton Centre , Redcar , Cleveland TS10 4RF , United Kingdom.
  • Bladen CL; d Absolute Antibody, Wilton Centre , Redcar , Cleveland TS10 4RF , United Kingdom.
  • Jones B; e NeoBiotechnologies , 2 Union Square, Union City , CA , USA.
  • Aldred SF; b SwitchGear Genomics , 1914 Palomar Oaks Way, Carlsbad , CA USA.
  • Bestagno M; f International Centre for Genetic Engineering and Biotechnology (ICGEB) , Padriciano 99, Trieste , Italy.
  • Burrone O; f International Centre for Genetic Engineering and Biotechnology (ICGEB) , Padriciano 99, Trieste , Italy.
  • Maynard J; g The University of Texas at Austin, Cockrell School of Engineering , McKetta Department of Chemical Engineering , 200 E Dean Keeton St. Stop C0400, Austin , Texas , USA.
  • Ferrara F; a Specifica Inc. , 1512 Pacheco St, Santa Fe , NM , USA.
  • Trimmer JS; h Department of Physiology and Membrane Biology , University of California , Davis, One Shields Avenue, Davis , CA , USA.
  • Görnemann J; i Institute for Molecular Genetics , University of Heidelberg , Im Neuenheimer Field 260, Heidelberg , Germany.
  • Glanville J; j Stanford University, School of Medicine , Stanford , California , USA.
  • Wolf P; k Department of Urology , Medical Center, University of Freiburg , Breisacher Str. 66, Freiburg , Germany.
  • Frenzel A; l Yumab GmbH , Inhoffenstr. 7, Braunschweig , Germany.
  • Wong J; p Technische Universität Braunschweig, Institute of Biochemistry, Biotechnology and Bioinformatics , Spielmannstr. 7, Braunschweig , Germany.
  • Koh XY; m A*Star p53 laboratory , 06-06 Immunos, Singapore , Singapore.
  • Eng HY; m A*Star p53 laboratory , 06-06 Immunos, Singapore , Singapore.
  • Lane D; m A*Star p53 laboratory , 06-06 Immunos, Singapore , Singapore.
  • Lefranc MP; m A*Star p53 laboratory , 06-06 Immunos, Singapore , Singapore.
  • Clark M; n IMGT®, the international ImMunoGeneTics information system®, Laboratoire d'ImmunoGénétique Moléculaire LIGM, Institut de Génétique Humaine IGH, UPR CNRS 1142, Montpellier University , Montpellier cedex 5 , France.
  • Dübel S; o Clark Antibodies Ltd , 10 Wellington Street, Cambridge , CB1 1HW , United Kingdom.
MAbs ; 10(4): 539-546, 2018.
Article em En | MEDLINE | ID: mdl-29485921

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Hibridomas / Anticorpos Monoclonais / Especificidade de Anticorpos Tipo de estudo: Clinical_trials / Prognostic_studies / Risk_factors_studies Limite: Animals / Humans Idioma: En Revista: MAbs Assunto da revista: ALERGIA E IMUNOLOGIA Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Estados Unidos

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Hibridomas / Anticorpos Monoclonais / Especificidade de Anticorpos Tipo de estudo: Clinical_trials / Prognostic_studies / Risk_factors_studies Limite: Animals / Humans Idioma: En Revista: MAbs Assunto da revista: ALERGIA E IMUNOLOGIA Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Estados Unidos