The sensitivity and specificity of touch preparation for rapid diagnosis of invasive fungal sinusitis: A pilot study.
Ear Nose Throat J
; 97(1-2): E32-E36, 2018.
Article
em En
| MEDLINE
| ID: mdl-29493729
ABSTRACT
Invasive fungal sinusitis is a morbid pathology that typically affects immunocompromised patients and may quickly progress to fulminant disease. The purpose of this study was to measure the sensitivity and specificity of touch preparation of nasal debridement specimens as a rapid diagnostic tool for invasive fungal sinusitis. A retrospective chart review was performed of 22 patients undergoing nasal debridement due to suspicion for invasive fungal sinusitis over a 10-year period. Thirteen patients had touch preparation of nasal specimens followed by routine histologic processing; 2 of these patients underwent two and 1 patient had three separate debridements, for a total of 17 touch preparations performed. The sensitivity and specificity of touch preparation were calculated by correlating the initial results with the presence of fungal invasion on final pathologic analysis. The sensitivity of touch preparation was 56% (95% confidence interval [CI] 0.23 to 0.85), specificity was 100% (95% CI 0.60 to 1.00), positive predictive value was 100% (95% CI 0.46 to 1.00), and negative predictive value was 67% (95% CI 0.35 to 0.89). This procedure may be a useful adjunct in situations requiring rapid diagnosis of invasive fungal sinusitis but should not be used as the sole criterion for determining the need for surgical intervention.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Sinusite
/
Técnicas de Tipagem Micológica
/
Infecções Fúngicas Invasivas
Tipo de estudo:
Diagnostic_studies
/
Evaluation_studies
/
Observational_studies
/
Prognostic_studies
/
Risk_factors_studies
Limite:
Adolescent
/
Adult
/
Female
/
Humans
/
Male
/
Middle aged
Idioma:
En
Revista:
Ear Nose Throat J
Ano de publicação:
2018
Tipo de documento:
Article
País de afiliação:
Estados Unidos