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BEST1 gene therapy corrects a diffuse retina-wide microdetachment modulated by light exposure.
Guziewicz, Karina E; Cideciyan, Artur V; Beltran, William A; Komáromy, András M; Dufour, Valerie L; Swider, Malgorzata; Iwabe, Simone; Sumaroka, Alexander; Kendrick, Brian T; Ruthel, Gordon; Chiodo, Vince A; Héon, Elise; Hauswirth, William W; Jacobson, Samuel G; Aguirre, Gustavo D.
Afiliação
  • Guziewicz KE; Division of Experimental Retinal Therapies, Department of Clinical Sciences and Advanced Medicine, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, PA 19104; karinag@vet.upenn.edu cideciya@pennmedicine.upenn.edu.
  • Cideciyan AV; Scheie Eye Institute, Department of Ophthalmology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104; karinag@vet.upenn.edu cideciya@pennmedicine.upenn.edu.
  • Beltran WA; Division of Experimental Retinal Therapies, Department of Clinical Sciences and Advanced Medicine, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, PA 19104.
  • Komáromy AM; Division of Experimental Retinal Therapies, Department of Clinical Sciences and Advanced Medicine, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, PA 19104.
  • Dufour VL; Department of Small Animal Clinical Sciences, College of Veterinary Medicine, Michigan State University, East Lansing, MI 48824.
  • Swider M; Division of Experimental Retinal Therapies, Department of Clinical Sciences and Advanced Medicine, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, PA 19104.
  • Iwabe S; Scheie Eye Institute, Department of Ophthalmology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104.
  • Sumaroka A; Division of Experimental Retinal Therapies, Department of Clinical Sciences and Advanced Medicine, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, PA 19104.
  • Kendrick BT; Scheie Eye Institute, Department of Ophthalmology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104.
  • Ruthel G; Division of Experimental Retinal Therapies, Department of Clinical Sciences and Advanced Medicine, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, PA 19104.
  • Chiodo VA; Department of Pathobiology, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, PA 19104.
  • Héon E; Department of Ophthalmology, College of Medicine, University of Florida, Gainesville, FL 32611.
  • Hauswirth WW; Department of Ophthalmology and Vision Sciences, The Hospital for Sick Children, University of Toronto, Toronto, ON M5G 2L3, Canada.
  • Jacobson SG; Department of Ophthalmology, College of Medicine, University of Florida, Gainesville, FL 32611.
  • Aguirre GD; Scheie Eye Institute, Department of Ophthalmology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104.
Proc Natl Acad Sci U S A ; 115(12): E2839-E2848, 2018 03 20.
Article em En | MEDLINE | ID: mdl-29507198

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Doenças Retinianas / Terapia Genética / Oftalmopatias Hereditárias / Bestrofinas Limite: Animals / Female / Humans / Male Idioma: En Revista: Proc Natl Acad Sci U S A Ano de publicação: 2018 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Doenças Retinianas / Terapia Genética / Oftalmopatias Hereditárias / Bestrofinas Limite: Animals / Female / Humans / Male Idioma: En Revista: Proc Natl Acad Sci U S A Ano de publicação: 2018 Tipo de documento: Article