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A novel regimen for relapsed/refractory adult acute myeloid leukemia using a KMT2A partial tandem duplication targeted therapy: results of phase 1 study NCI 8485.
Mims, Alice S; Mishra, Anjali; Orwick, Shelley; Blachly, James; Klisovic, Rebecca B; Garzon, Ramiro; Walker, Alison R; Devine, Steven M; Walsh, Katherine J; Vasu, Sumithira; Whitman, Susan; Marcucci, Guido; Jones, Daniel; Heerema, Nyla A; Lozanski, Gerard; Caligiuri, Michael A; Bloomfield, Clara D; Byrd, John C; Piekarz, Richard; Grever, Michael R; Blum, William.
Afiliação
  • Mims AS; Division of Hematology, Department of Medicine, The Ohio State University and The Ohio State University Comprehensive Cancer Center, Columbus, OH alice.mims@osumc.edu.
  • Mishra A; Department of Medicine, The Ohio State University and The Ohio State University Comprehensive Cancer Center, Columbus, OH.
  • Orwick S; Department of Medicine, The Ohio State University and The Ohio State University Comprehensive Cancer Center, Columbus, OH.
  • Blachly J; Division of Hematology, Department of Medicine, The Ohio State University and The Ohio State University Comprehensive Cancer Center, Columbus, OH.
  • Klisovic RB; Department of Hematology and Medical Oncology, Emory University School of Medicine, Winship Cancer Institute, Atlanta, GA.
  • Garzon R; Division of Hematology, Department of Medicine, The Ohio State University and The Ohio State University Comprehensive Cancer Center, Columbus, OH.
  • Walker AR; Division of Hematology, Department of Medicine, The Ohio State University and The Ohio State University Comprehensive Cancer Center, Columbus, OH.
  • Devine SM; Division of Hematology, Department of Medicine, The Ohio State University and The Ohio State University Comprehensive Cancer Center, Columbus, OH.
  • Walsh KJ; Division of Hematology, Department of Medicine, The Ohio State University and The Ohio State University Comprehensive Cancer Center, Columbus, OH.
  • Vasu S; Division of Hematology, Department of Medicine, The Ohio State University and The Ohio State University Comprehensive Cancer Center, Columbus, OH.
  • Whitman S; Department of Medicine, The Ohio State University and The Ohio State University Comprehensive Cancer Center, Columbus, OH.
  • Marcucci G; Department of Hematology and Hematopoietic Cell Transplantation, City of Hope National Medical Center, Duarte, CA.
  • Jones D; Department of Pathology, The Ohio State University and The Ohio State University Comprehensive Cancer Center, Columbus, OH.
  • Heerema NA; Department of Pathology, The Ohio State University and The Ohio State University Comprehensive Cancer Center, Columbus, OH.
  • Lozanski G; Department of Pathology, The Ohio State University and The Ohio State University Comprehensive Cancer Center, Columbus, OH.
  • Caligiuri MA; Department of Medicine, The Ohio State University and The Ohio State University Comprehensive Cancer Center, Columbus, OH.
  • Bloomfield CD; Division of Hematology, Department of Medicine, The Ohio State University and The Ohio State University Comprehensive Cancer Center, Columbus, OH.
  • Byrd JC; Division of Hematology, Department of Medicine, The Ohio State University and The Ohio State University Comprehensive Cancer Center, Columbus, OH.
  • Piekarz R; Investigational Drug Branch of CTEP, National Cancer Institute, Bethesda, MD, USA.
  • Grever MR; Division of Hematology, Department of Medicine, The Ohio State University and The Ohio State University Comprehensive Cancer Center, Columbus, OH.
  • Blum W; Department of Hematology and Medical Oncology, Emory University School of Medicine, Winship Cancer Institute, Atlanta, GA.
Haematologica ; 103(6): 982-987, 2018 06.
Article em En | MEDLINE | ID: mdl-29567781

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Leucemia Mieloide Aguda / Protocolos de Quimioterapia Combinada Antineoplásica / Histona-Lisina N-Metiltransferase / Duplicação Gênica / Sequências de Repetição em Tandem / Proteína de Leucina Linfoide-Mieloide Tipo de estudo: Diagnostic_studies / Guideline / Prognostic_studies Limite: Adult / Female / Humans / Male / Middle aged Idioma: En Revista: Haematologica Ano de publicação: 2018 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Leucemia Mieloide Aguda / Protocolos de Quimioterapia Combinada Antineoplásica / Histona-Lisina N-Metiltransferase / Duplicação Gênica / Sequências de Repetição em Tandem / Proteína de Leucina Linfoide-Mieloide Tipo de estudo: Diagnostic_studies / Guideline / Prognostic_studies Limite: Adult / Female / Humans / Male / Middle aged Idioma: En Revista: Haematologica Ano de publicação: 2018 Tipo de documento: Article