Chloride imbalance is involved in the pathogenesis of optic neuritis in neuromyelitis optica.
J Neuroimmunol
; 320: 98-100, 2018 07 15.
Article
em En
| MEDLINE
| ID: mdl-29572032
ABSTRACT
Chloride imbalance between the serum and the cerebrospinal fluid (CSF) has been recently shown to exist in the acute phase of neuromyelitis optica (NMO). In this report, we studied the relation between the quotient of chloride (QCl) and the severity of optic neuritis (ON) in NMO patients. There was a positive correlation (Râ¯=â¯0.67; pâ¯<â¯0.05) between QCl and the length of ON-lesion. The visual prognosis also showed a positive correlation with QCl in the acute phase (Râ¯=â¯0.58; pâ¯<â¯0.05). These results support the theory that chloride imbalance between serum and CSF may trigger the ON in NMO spectrum disorders.
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Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Cloretos
/
Neurite Óptica
/
Neuromielite Óptica
Tipo de estudo:
Etiology_studies
Limite:
Humans
Idioma:
En
Revista:
J Neuroimmunol
Ano de publicação:
2018
Tipo de documento:
Article