Tumour motion of oesophageal squamous cell carcinoma evaluated by cine MRI: associated with tumour location.
Clin Radiol
; 73(7): 676.e1-676.e7, 2018 07.
Article
em En
| MEDLINE
| ID: mdl-29573787
ABSTRACT
AIM:
To evaluate the association between oesophageal tumour motion and tumour location using cine magnetic resonance imaging (MRI). MATERIALS ANDMETHODS:
Thirty-three consecutive patients with oesophageal squamous cell carcinoma were enrolled, and underwent cine MRI of oesophageal tumours. The maximum displacements in the anterior-posterior (A-P), superior-inferior (S-I), and left-right (L-R) directions of the tumours were assessed statistically to show their associations with tumour location.RESULTS:
Tumour motion in A-P and S-I directions increased from upper to lower oesophagus (r=0.505, p=0.003; and r=0.600, p<0.001, respectively). In A-P and S-I directions, tumours showed larger motion in the lower oesophagus than in the upper or middle oesophagus (all p<0.05). Motion of middle and lower oesophageal tumours in the S-I direction was larger than in L-R or A-P direction (all p<0.05). To provide 95% geometric coverage for the motion of upper oesophageal tumours, statistical analysis showed margins of 3.75 mm in L-R direction, 3.72 mm in A-P direction, and 5.38 mm in S-I direction. For the motion of tumours of the middle oesophagus, 95% coverage required margins of 8.50, 6.62, and 11.96 mm in L-R, A-P, and S-I directions, respectively, and for lower oesophageal tumours, 95% coverage required margins of 9.17, 9.68, and 12.98 mm in L-R, A-P, and S-I direction, respectively.CONCLUSION:
Oesophageal tumour motion in different directions can be associated with tumour location as shown on cine MRI, suggesting that the present findings could be helpful for better understanding oesophageal tumour motion and gating individualised radiation delivery strategies.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Neoplasias Esofágicas
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Interpretação de Imagem Assistida por Computador
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Imagem Cinética por Ressonância Magnética
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Carcinoma de Células Escamosas do Esôfago
Tipo de estudo:
Risk_factors_studies
Limite:
Aged
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Female
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Humans
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Male
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Middle aged
Idioma:
En
Revista:
Clin Radiol
Ano de publicação:
2018
Tipo de documento:
Article
País de afiliação:
China