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Anti-CTLA-4 therapy requires an Fc domain for efficacy.
Ingram, Jessica R; Blomberg, Olga S; Rashidian, Mohammad; Ali, Lestat; Garforth, Scott; Fedorov, Elena; Fedorov, Alexander A; Bonanno, Jeffrey B; Le Gall, Camille; Crowley, Stephanie; Espinosa, Camilo; Biary, Tamara; Keliher, Edmund J; Weissleder, Ralph; Almo, Steven C; Dougan, Stephanie K; Ploegh, Hidde L; Dougan, Michael.
Afiliação
  • Ingram JR; Department of Cancer Immunology and Virology, Dana-Farber Cancer Institute, Boston, MA 02215.
  • Blomberg OS; Program in Cellular and Molecular Medicine, Children's Hospital Boston, Boston, MA 02115.
  • Rashidian M; Program in Cellular and Molecular Medicine, Children's Hospital Boston, Boston, MA 02115.
  • Ali L; Department of Cancer Immunology and Virology, Dana-Farber Cancer Institute, Boston, MA 02215.
  • Garforth S; Department of Biochemistry, Albert Einstein College of Medicine, Bronx, NY 10461.
  • Fedorov E; Department of Biochemistry, Albert Einstein College of Medicine, Bronx, NY 10461.
  • Fedorov AA; Department of Biochemistry, Albert Einstein College of Medicine, Bronx, NY 10461.
  • Bonanno JB; Department of Biochemistry, Albert Einstein College of Medicine, Bronx, NY 10461.
  • Le Gall C; Program in Cellular and Molecular Medicine, Children's Hospital Boston, Boston, MA 02115.
  • Crowley S; Department of Cancer Immunology and Virology, Dana-Farber Cancer Institute, Boston, MA 02215.
  • Espinosa C; Department of Cancer Immunology and Virology, Dana-Farber Cancer Institute, Boston, MA 02215.
  • Biary T; Division of Gastroenterology, Massachusetts General Hospital, Boston, MA 02114.
  • Keliher EJ; Center for Systems Biology, Massachusetts General Hospital, Boston, MA 02114.
  • Weissleder R; Department of Radiology, Massachusetts General Hospital, Boston, MA 02114.
  • Almo SC; Center for Systems Biology, Massachusetts General Hospital, Boston, MA 02114.
  • Dougan SK; Department of Radiology, Massachusetts General Hospital, Boston, MA 02114.
  • Ploegh HL; Department of Biochemistry, Albert Einstein College of Medicine, Bronx, NY 10461.
  • Dougan M; Department of Cancer Immunology and Virology, Dana-Farber Cancer Institute, Boston, MA 02215.
Proc Natl Acad Sci U S A ; 115(15): 3912-3917, 2018 04 10.
Article em En | MEDLINE | ID: mdl-29581255

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Fragmentos Fc das Imunoglobulinas / Fragmentos de Imunoglobulinas / Antígeno CTLA-4 / Neoplasias Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Revista: Proc Natl Acad Sci U S A Ano de publicação: 2018 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Fragmentos Fc das Imunoglobulinas / Fragmentos de Imunoglobulinas / Antígeno CTLA-4 / Neoplasias Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Revista: Proc Natl Acad Sci U S A Ano de publicação: 2018 Tipo de documento: Article