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A Huntingtin Knockin Pig Model Recapitulates Features of Selective Neurodegeneration in Huntington's Disease.
Yan, Sen; Tu, Zhuchi; Liu, Zhaoming; Fan, Nana; Yang, Huiming; Yang, Su; Yang, Weili; Zhao, Yu; Ouyang, Zhen; Lai, Chengdan; Yang, Huaqiang; Li, Li; Liu, Qishuai; Shi, Hui; Xu, Guangqing; Zhao, Heng; Wei, Hongjiang; Pei, Zhong; Li, Shihua; Lai, Liangxue; Li, Xiao-Jiang.
Afiliação
  • Yan S; Ministry of Education CNS Regeneration Collaborative Joint Laboratory, Guangdong-Hongkong-Macau Institute of CNS Regeneration, Jinan University, 510632 Guangzhou, China.
  • Tu Z; Ministry of Education CNS Regeneration Collaborative Joint Laboratory, Guangdong-Hongkong-Macau Institute of CNS Regeneration, Jinan University, 510632 Guangzhou, China.
  • Liu Z; Key Laboratory of Regenerative Biology, South China Institute for Stem Cell, Biology and Regenerative Medicine, Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences, 510530 Guangzhou, China.
  • Fan N; Key Laboratory of Regenerative Biology, South China Institute for Stem Cell, Biology and Regenerative Medicine, Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences, 510530 Guangzhou, China.
  • Yang H; Department of Human Genetics, Emory University School of Medicine, Atlanta, GA 30322, USA.
  • Yang S; Department of Human Genetics, Emory University School of Medicine, Atlanta, GA 30322, USA.
  • Yang W; Ministry of Education CNS Regeneration Collaborative Joint Laboratory, Guangdong-Hongkong-Macau Institute of CNS Regeneration, Jinan University, 510632 Guangzhou, China.
  • Zhao Y; Key Laboratory of Regenerative Biology, South China Institute for Stem Cell, Biology and Regenerative Medicine, Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences, 510530 Guangzhou, China.
  • Ouyang Z; Key Laboratory of Regenerative Biology, South China Institute for Stem Cell, Biology and Regenerative Medicine, Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences, 510530 Guangzhou, China.
  • Lai C; Key Laboratory of Regenerative Biology, South China Institute for Stem Cell, Biology and Regenerative Medicine, Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences, 510530 Guangzhou, China.
  • Yang H; Key Laboratory of Regenerative Biology, South China Institute for Stem Cell, Biology and Regenerative Medicine, Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences, 510530 Guangzhou, China.
  • Li L; Key Laboratory of Regenerative Biology, South China Institute for Stem Cell, Biology and Regenerative Medicine, Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences, 510530 Guangzhou, China.
  • Liu Q; Key Laboratory of Regenerative Biology, South China Institute for Stem Cell, Biology and Regenerative Medicine, Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences, 510530 Guangzhou, China.
  • Shi H; Key Laboratory of Regenerative Biology, South China Institute for Stem Cell, Biology and Regenerative Medicine, Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences, 510530 Guangzhou, China.
  • Xu G; Department of Neurology, the First Affiliated Hospital of Sun Yat-Sen University, Guangzhou, 510080 Guangdong, China.
  • Zhao H; College of Animal Science and Technology, Yunnan Agricultural University, 650201 Kunming, China.
  • Wei H; College of Animal Science and Technology, Yunnan Agricultural University, 650201 Kunming, China.
  • Pei Z; Department of Neurology, the First Affiliated Hospital of Sun Yat-Sen University, Guangzhou, 510080 Guangdong, China.
  • Li S; Ministry of Education CNS Regeneration Collaborative Joint Laboratory, Guangdong-Hongkong-Macau Institute of CNS Regeneration, Jinan University, 510632 Guangzhou, China; Department of Human Genetics, Emory University School of Medicine, Atlanta, GA 30322, USA. Electronic address: sli@emory.edu.
  • Lai L; Key Laboratory of Regenerative Biology, South China Institute for Stem Cell, Biology and Regenerative Medicine, Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences, 510530 Guangzhou, China; Jilin Provincial Key Laboratory of Animal Embryo Engineering, Institute of Zoonosis, C
  • Li XJ; Ministry of Education CNS Regeneration Collaborative Joint Laboratory, Guangdong-Hongkong-Macau Institute of CNS Regeneration, Jinan University, 510632 Guangzhou, China; Department of Human Genetics, Emory University School of Medicine, Atlanta, GA 30322, USA. Electronic address: xli2@emory.edu.
Cell ; 173(4): 989-1002.e13, 2018 05 03.
Article em En | MEDLINE | ID: mdl-29606351

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Doença de Huntington / Proteína Huntingtina Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Revista: Cell Ano de publicação: 2018 Tipo de documento: Article País de afiliação: China

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Doença de Huntington / Proteína Huntingtina Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Revista: Cell Ano de publicação: 2018 Tipo de documento: Article País de afiliação: China