Contribution of Adrenal Glands to Intratumor Androgens and Growth of Castration-Resistant Prostate Cancer.

Mostaghel, Elahe A; Zhang, Ailin; Hernandez, Susana; Marck, Brett T; Zhang, Xiaotun; Tamae, Daniel; Biehl, Heather E; Tretiakova, Maria; Bartlett, Jon; Burns, John; Dumpit, Ruth; Ang, Lisa; Matsumoto, Alvin M; Penning, Trevor M; Balk, Steven P; Morrissey, Colm; Corey, Eva; True, Lawrence D; Nelson, Peter S

Mostaghel, Elahe A; Zhang, Ailin; Hernandez, Susana; Marck, Brett T; Zhang, Xiaotun; Tamae, Daniel; Biehl, Heather E; Tretiakova, Maria; Bartlett, Jon; Burns, John; Dumpit, Ruth; Ang, Lisa; Matsumoto, Alvin M; Penning, Trevor M; Balk, Steven P; Morrissey, Colm; Corey, Eva; True, Lawrence D; Nelson, Peter S.

Afiliação

Mostaghel EA; Geriatric Research, Education and Clinical Center, VA Puget Sound Health Care System, Seattle, Washington. emostagh@fredhutch.org.
Zhang A; Fred Hutchinson Cancer Research Center, Seattle, Washington.
Hernandez S; Fred Hutchinson Cancer Research Center, Seattle, Washington.
Marck BT; Fred Hutchinson Cancer Research Center, Seattle, Washington.
Zhang X; Geriatric Research, Education and Clinical Center, VA Puget Sound Health Care System, Seattle, Washington.
Tamae D; Department of Urology, University of Washington, Seattle, Washington.
Biehl HE; Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania.
Tretiakova M; Fred Hutchinson Cancer Research Center, Seattle, Washington.
Bartlett J; Department of Pathology, University of Washington, Seattle, Washington.
Burns J; Fred Hutchinson Cancer Research Center, Seattle, Washington.
Dumpit R; Fred Hutchinson Cancer Research Center, Seattle, Washington.
Ang L; Fred Hutchinson Cancer Research Center, Seattle, Washington.
Matsumoto AM; Fred Hutchinson Cancer Research Center, Seattle, Washington.
Penning TM; Geriatric Research, Education and Clinical Center, VA Puget Sound Health Care System, Seattle, Washington.
Balk SP; Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania.
Morrissey C; Beth Israel Deaconess Medical Center, Boston, Massachusetts.
Corey E; Department of Urology, University of Washington, Seattle, Washington.
True LD; Department of Urology, University of Washington, Seattle, Washington.
Nelson PS; Department of Pathology, University of Washington, Seattle, Washington.

Clin Cancer Res ; 25(1): 426-439, 2019 01 01.

Article em En | MEDLINE | ID: mdl-30181386

Assuntos

Androgênios/genética; Proliferação de Células/genética; Neoplasias de Próstata Resistentes à Castração/genética; Receptores Androgênicos/genética; 17-Hidroxiesteroide Desidrogenases/genética; Glândulas Suprarrenais/patologia; Glândulas Suprarrenais/cirurgia; Adrenalectomia; Membro C3 da Família 1 de alfa-Ceto Redutase/genética; Androgênios/biossíntese; Animais; Linhagem Celular Tumoral; Regulação Neoplásica da Expressão Gênica; Xenoenxertos; Humanos; Masculino; Camundongos; Complexos Multienzimáticos/genética; Recidiva Local de Neoplasia; Progesterona Redutase/genética; Neoplasias de Próstata Resistentes à Castração/patologia; Neoplasias de Próstata Resistentes à Castração/cirurgia; Esteroide 17-alfa-Hidroxilase/genética; Esteroide Isomerases/genética; Testosterona/genética; Testosterona/metabolismo

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Receptores Androgênicos / Proliferação de Células / Neoplasias de Próstata Resistentes à Castração / Androgênios Limite: Animals / Humans / Male Idioma: En Revista: Clin Cancer Res Assunto da revista: NEOPLASIAS Ano de publicação: 2019 Tipo de documento: Article

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