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Pre-existing antiacetylcholine receptor autoantibodies and B cell lymphopaenia are associated with the development of myositis in patients with thymoma treated with avelumab, an immune checkpoint inhibitor targeting programmed death-ligand 1.
Mammen, Andrew L; Rajan, Arun; Pak, Katherine; Lehky, Tanya; Casciola-Rosen, Livia; Donahue, Renee N; Lepone, Lauren M; Zekeridou, Anastasia; Pittock, Sean J; Hassan, Raffit; Schlom, Jeffrey; Gulley, James L.
Afiliação
  • Mammen AL; Laboratory of Muscle Stem Cells and Gene Regulation, National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Institutes of Health, Bethesda, Maryland, USA andrew.mammen@nih.gov.
  • Rajan A; Thoracic and Gastrointestinal Oncology Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, USA.
  • Pak K; Laboratory of Muscle Stem Cells and Gene Regulation, National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Institutes of Health, Bethesda, Maryland, USA.
  • Lehky T; Electromyography Section, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, Maryland, USA.
  • Casciola-Rosen L; Division of Rheumatology, Department of Medicine, The Johns Hopkins Hospital, Baltimore, Maryland, USA.
  • Donahue RN; Laboratory of Tumor Immunology and Biology, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, USA.
  • Lepone LM; Laboratory of Tumor Immunology and Biology, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, USA.
  • Zekeridou A; Neuroimmunology Laboratory, Mayo Clinic, Rochester, Minnesota, USA.
  • Pittock SJ; Neuroimmunology Laboratory, Mayo Clinic, Rochester, Minnesota, USA.
  • Hassan R; Thoracic and Gastrointestinal Oncology Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, USA.
  • Schlom J; Laboratory of Tumor Immunology and Biology, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, USA.
  • Gulley JL; Laboratory of Tumor Immunology and Biology, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, USA.
Ann Rheum Dis ; 78(1): 150-152, 2019 01.
Article em En | MEDLINE | ID: mdl-30185415
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Autoanticorpos / Timoma / Neoplasias do Timo / Receptores Colinérgicos / Linfopenia / Anticorpos Monoclonais / Miosite Tipo de estudo: Etiology_studies / Risk_factors_studies Limite: Humans Idioma: En Revista: Ann Rheum Dis Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Estados Unidos
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Autoanticorpos / Timoma / Neoplasias do Timo / Receptores Colinérgicos / Linfopenia / Anticorpos Monoclonais / Miosite Tipo de estudo: Etiology_studies / Risk_factors_studies Limite: Humans Idioma: En Revista: Ann Rheum Dis Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Estados Unidos