The Action of the Hexokinase Inhibitor 2-deoxy-d-glucose on Cryptosporidium parvum and the Discovery of Activities against the Parasite Hexokinase from Marketed Drugs.

Eltahan, Rana; Guo, Fengguang; Zhang, Haili; Zhu, Guan

Eltahan, Rana; Guo, Fengguang; Zhang, Haili; Zhu, Guan.

Afiliação

Eltahan R; Department of Veterinary Pathobiology, College of Veterinary Medicine & Biomedical Sciences, Texas A&M University, College Station, Texas, 77843-4467.
Guo F; Department of Veterinary Pathobiology, College of Veterinary Medicine & Biomedical Sciences, Texas A&M University, College Station, Texas, 77843-4467.
Zhang H; Department of Veterinary Pathobiology, College of Veterinary Medicine & Biomedical Sciences, Texas A&M University, College Station, Texas, 77843-4467.
Zhu G; Department of Veterinary Pathobiology, College of Veterinary Medicine & Biomedical Sciences, Texas A&M University, College Station, Texas, 77843-4467.

J Eukaryot Microbiol ; 66(3): 460-468, 2019 05.

Article em En | MEDLINE | ID: mdl-30222231

Assuntos

Antiprotozoários/farmacologia; Cryptosporidium parvum/efeitos dos fármacos; Desoxiglucose/farmacologia; Glucose-6-Fosfato/análogos & derivados; Hexoquinase/metabolismo; Proteínas de Protozoários/metabolismo; Cryptosporidium parvum/enzimologia; Glucose-6-Fosfato/metabolismo; Glucose-6-Fosfato Isomerase/metabolismo; Fosforilação

Palavras-chave

Apicomplexan; drug target

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proteínas de Protozoários / Cryptosporidium parvum / Glucose-6-Fosfato / Desoxiglucose / Hexoquinase / Antiprotozoários Tipo de estudo: Prognostic_studies Idioma: En Revista: J Eukaryot Microbiol Assunto da revista: MICROBIOLOGIA / PARASITOLOGIA Ano de publicação: 2019 Tipo de documento: Article

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