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Sustained activation of the Aryl hydrocarbon Receptor transcription factor promotes resistance to BRAF-inhibitors in melanoma.
Corre, Sébastien; Tardif, Nina; Mouchet, Nicolas; Leclair, Héloïse M; Boussemart, Lise; Gautron, Arthur; Bachelot, Laura; Perrot, Anthony; Soshilov, Anatoly; Rogiers, Aljosja; Rambow, Florian; Dumontet, Erwan; Tarte, Karin; Bessede, Alban; Guillemin, Gilles J; Marine, Jean-Christophe; Denison, Michael S; Gilot, David; Galibert, Marie-Dominique.
Afiliação
  • Corre S; IGDR (Institut de Génétique et Développement de Rennes)-UMR6290, CNRS, Univ Rennes, F-35000, Rennes, France. sebastien.corre@univ-rennes1.fr.
  • Tardif N; IGDR (Institut de Génétique et Développement de Rennes)-UMR6290, CNRS, Univ Rennes, F-35000, Rennes, France.
  • Mouchet N; IGDR (Institut de Génétique et Développement de Rennes)-UMR6290, CNRS, Univ Rennes, F-35000, Rennes, France.
  • Leclair HM; IGDR (Institut de Génétique et Développement de Rennes)-UMR6290, CNRS, Univ Rennes, F-35000, Rennes, France.
  • Boussemart L; IGDR (Institut de Génétique et Développement de Rennes)-UMR6290, CNRS, Univ Rennes, F-35000, Rennes, France.
  • Gautron A; Department of Dermatology, Hospital University of Rennes (CHU Rennes), F-35000, Rennes, France.
  • Bachelot L; IGDR (Institut de Génétique et Développement de Rennes)-UMR6290, CNRS, Univ Rennes, F-35000, Rennes, France.
  • Perrot A; IGDR (Institut de Génétique et Développement de Rennes)-UMR6290, CNRS, Univ Rennes, F-35000, Rennes, France.
  • Soshilov A; IGDR (Institut de Génétique et Développement de Rennes)-UMR6290, CNRS, Univ Rennes, F-35000, Rennes, France.
  • Rogiers A; Department of Environmental Toxicology, University of California, Meyer Hall, Davis, CA, 95616, USA.
  • Rambow F; Laboratory for Molecular Cancer Biology, VIB Center for Cancer Biology, VIB, Leuven, 3000, Belgium.
  • Dumontet E; Laboratory for Molecular Cancer Biology, Department of Oncology, KU Leuven, Leuven, 3000, Belgium.
  • Tarte K; Laboratory for Molecular Cancer Biology, VIB Center for Cancer Biology, VIB, Leuven, 3000, Belgium.
  • Bessede A; Laboratory for Molecular Cancer Biology, Department of Oncology, KU Leuven, Leuven, 3000, Belgium.
  • Guillemin GJ; MICMAC (MIcroenvironment, Cell differentiation, iMmunology And Cancer)-UMR_S 1236, Inserm, Univ Rennes, F-35000, Rennes, France.
  • Marine JC; MICMAC (MIcroenvironment, Cell differentiation, iMmunology And Cancer)-UMR_S 1236, Inserm, Univ Rennes, F-35000, Rennes, France.
  • Denison MS; ImmuSmol, Pessac, F-33600, France.
  • Gilot D; Neuroinflammation Group, MND and Neurodegenerative Diseases Research Center, Macquarie University, Sydney, NSW, 2109, Australia.
  • Galibert MD; Laboratory for Molecular Cancer Biology, VIB Center for Cancer Biology, VIB, Leuven, 3000, Belgium.
Nat Commun ; 9(1): 4775, 2018 11 14.
Article em En | MEDLINE | ID: mdl-30429474
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias Cutâneas / Receptores de Hidrocarboneto Arílico / Resistencia a Medicamentos Antineoplásicos / Proteínas Proto-Oncogênicas B-raf / Inibidores de Proteínas Quinases / Melanoma Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Revista: Nat Commun Assunto da revista: BIOLOGIA / CIENCIA Ano de publicação: 2018 Tipo de documento: Article País de afiliação: França
Texto completo
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XML
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias Cutâneas / Receptores de Hidrocarboneto Arílico / Resistencia a Medicamentos Antineoplásicos / Proteínas Proto-Oncogênicas B-raf / Inibidores de Proteínas Quinases / Melanoma Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Revista: Nat Commun Assunto da revista: BIOLOGIA / CIENCIA Ano de publicação: 2018 Tipo de documento: Article País de afiliação: França