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The connexin26 human mutation N14K disrupts cytosolic intersubunit interactions and promotes channel opening.
Valdez Capuccino, Juan M; Chatterjee, Payal; García, Isaac E; Botello-Smith, Wesley M; Zhang, Han; Harris, Andrew L; Luo, Yun; Contreras, Jorge E.
Afiliação
  • Valdez Capuccino JM; Department of Pharmacology, Physiology & Neuroscience, New Jersey Medical School, Rutgers University, Newark, NJ.
  • Chatterjee P; Department of Pharmaceutical Sciences, College of Pharmacy, Western University of Health Sciences, Pomona, CA.
  • García IE; Laboratory of Molecular Physiology and Biophysics, Facultad de Odontología, Universidad de Valparaíso, Valparaíso, Chile.
  • Botello-Smith WM; Centro Interdisciplinario de Neurociencias de Valparaíso, Universidad de Valparaíso, Valparaíso, Chile.
  • Zhang H; Department of Pharmaceutical Sciences, College of Pharmacy, Western University of Health Sciences, Pomona, CA.
  • Harris AL; Department of Pharmaceutical Sciences, College of Pharmacy, Western University of Health Sciences, Pomona, CA.
  • Luo Y; Department of Pharmacology, Physiology & Neuroscience, New Jersey Medical School, Rutgers University, Newark, NJ.
  • Contreras JE; Department of Pharmaceutical Sciences, College of Pharmacy, Western University of Health Sciences, Pomona, CA luoy@westernu.edu.
J Gen Physiol ; 151(3): 328-341, 2019 03 04.
Article em En | MEDLINE | ID: mdl-30530766
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Ativação do Canal Iônico / Mutação de Sentido Incorreto / Multimerização Proteica / Conexina 26 Limite: Animals / Humans Idioma: En Revista: J Gen Physiol Ano de publicação: 2019 Tipo de documento: Article
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Ativação do Canal Iônico / Mutação de Sentido Incorreto / Multimerização Proteica / Conexina 26 Limite: Animals / Humans Idioma: En Revista: J Gen Physiol Ano de publicação: 2019 Tipo de documento: Article