Degradation of T-Tubular Microdomains and Altered cAMP Compartmentation Lead to Emergence of Arrhythmogenic Triggers in Heart Failure Myocytes: An <i>in silico</i> Study.

Loucks, Alexandra D; O'Hara, Thomas; Trayanova, Natalia A

Degradation of T-Tubular Microdomains and Altered cAMP Compartmentation Lead to Emergence of Arrhythmogenic Triggers in Heart Failure Myocytes: An in silico Study.

Loucks, Alexandra D; O'Hara, Thomas; Trayanova, Natalia A.

Afiliação

Loucks AD; Institute for Computational Medicine and Department of Biomedical Engineering at Johns Hopkins University, Baltimore, MD, United States.
O'Hara T; Institute for Computational Medicine and Department of Biomedical Engineering at Johns Hopkins University, Baltimore, MD, United States.
Trayanova NA; Institute for Computational Medicine and Department of Biomedical Engineering at Johns Hopkins University, Baltimore, MD, United States.

Front Physiol ; 9: 1737, 2018.

Article em En | MEDLINE | ID: mdl-30564142

Palavras-chave

arrhythmia; computational modeling; early afterdepolarizations; heart failure; microdomain degradation

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Revista: Front Physiol Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Estados Unidos

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