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A distinct epigenetic profile distinguishes stenotic from non-inflamed fibroblasts in the ileal mucosa of Crohn's disease patients.
Li Yim, Andrew Y F; de Bruyn, Jessica R; Duijvis, Nicolette W; Sharp, Catriona; Ferrero, Enrico; de Jonge, Wouter J; Wildenberg, Manon E; Mannens, Marcel M A M; Buskens, Christianne J; D'Haens, Geert R; Henneman, Peter; Te Velde, Anje A.
Afiliação
  • Li Yim AYF; Genome Diagnostics Laboratory, Department of Clinical Genetics, Amsterdam UMC, University of Amsterdam, Amsterdam, the Netherlands.
  • de Bruyn JR; Epigenetics Discovery Performance Unit, GlaxoSmithKline, Stevenage, United Kingdom.
  • Duijvis NW; Tytgat Institute for Liver and Intestinal Research, Amsterdam UMC, University of Amsterdam, Amsterdam, the Netherlands.
  • Sharp C; Department of Gastroenterology, Amsterdam UMC, University of Amsterdam, Amsterdam, the Netherlands.
  • Ferrero E; Tytgat Institute for Liver and Intestinal Research, Amsterdam UMC, University of Amsterdam, Amsterdam, the Netherlands.
  • de Jonge WJ; Epigenetics Discovery Performance Unit, GlaxoSmithKline, Stevenage, United Kingdom.
  • Wildenberg ME; Computational Biology, Target Sciences, GlaxoSmithKline, Stevenage, United Kingdom.
  • Mannens MMAM; Tytgat Institute for Liver and Intestinal Research, Amsterdam UMC, University of Amsterdam, Amsterdam, the Netherlands.
  • Buskens CJ; Tytgat Institute for Liver and Intestinal Research, Amsterdam UMC, University of Amsterdam, Amsterdam, the Netherlands.
  • D'Haens GR; Genome Diagnostics Laboratory, Department of Clinical Genetics, Amsterdam UMC, University of Amsterdam, Amsterdam, the Netherlands.
  • Henneman P; Department of Surgery, Amsterdam UMC, University of Amsterdam, Amsterdam, the Netherlands.
  • Te Velde AA; Department of Gastroenterology, Amsterdam UMC, University of Amsterdam, Amsterdam, the Netherlands.
PLoS One ; 13(12): e0209656, 2018.
Article em En | MEDLINE | ID: mdl-30589872
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Doença de Crohn / Epigênese Genética / Transcriptoma / Mucosa Intestinal Limite: Adult / Aged / Humans / Middle aged Idioma: En Revista: PLoS One Assunto da revista: CIENCIA / MEDICINA Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Holanda
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Doença de Crohn / Epigênese Genética / Transcriptoma / Mucosa Intestinal Limite: Adult / Aged / Humans / Middle aged Idioma: En Revista: PLoS One Assunto da revista: CIENCIA / MEDICINA Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Holanda