Micro-solid phase extraction and LC-MS<sup>3</sup> for the determination of triptorelin in rat plasma and application to a pharmacokinetic study.

Ren, Tianming; Zhang, Zhi; Fawcett, John Paul; Sun, Dong; Gu, Jingkai

Micro-solid phase extraction and LC-MS³ for the determination of triptorelin in rat plasma and application to a pharmacokinetic study.

Ren, Tianming; Zhang, Zhi; Fawcett, John Paul; Sun, Dong; Gu, Jingkai.

Afiliação

Ren T; School of Life Sciences, Jilin University, Changchun, 130012, PR China.
Zhang Z; School of Life Sciences, Jilin University, Changchun, 130012, PR China.
Fawcett JP; School of Pharmacy, University of Otago, Dunedin, P.O. Box 56, New Zealand.
Sun D; Beijing Institute of Drug Metabolism, Beijing, 102209, PR China. Electronic address: dong_sun@web.de.
Gu J; School of Life Sciences, Jilin University, Changchun, 130012, PR China; Beijing Institute of Drug Metabolism, Beijing, 102209, PR China. Electronic address: gujk@jlu.edu.cn.

J Pharm Biomed Anal ; 166: 13-19, 2019 Mar 20.

Article em En | MEDLINE | ID: mdl-30599277

Assuntos

Microextração em Fase Sólida/métodos; Pamoato de Triptorrelina/farmacocinética; Animais; Cromatografia Líquida; Feminino; Limite de Detecção; Masculino; Ratos; Espectrometria de Massas em Tandem; Pamoato de Triptorrelina/sangue

Palavras-chave

LCMS(3); Micro-solid phase extraction; Pharmacokinetics; Second generation product ions; Triptorelin

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Pamoato de Triptorrelina / Microextração em Fase Sólida Limite: Animals Idioma: En Revista: J Pharm Biomed Anal Ano de publicação: 2019 Tipo de documento: Article

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