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Metabolism of remimazolam in primary human hepatocytes during continuous long-term infusion in a 3-D bioreactor system.
Freyer, Nora; Knöspel, Fanny; Damm, Georg; Greuel, Selina; Schneider, Christin; Seehofer, Daniel; Stöhr, Thomas; Petersen, Karl-Uwe; Zeilinger, Katrin.
Afiliação
  • Freyer N; Berlin Brandenburg Center for Regenerative Therapies (BCRT), Charité - Universitätsmedizin Berlin, Berlin 13353, Germany, nora-freyer@gmx.de.
  • Knöspel F; Berlin Brandenburg Center for Regenerative Therapies (BCRT), Charité - Universitätsmedizin Berlin, Berlin 13353, Germany, nora-freyer@gmx.de.
  • Damm G; Department of Hepatobiliary Surgery and Visceral Transplantation, University of Leipzig, Leipzig 04103, Germany.
  • Greuel S; Berlin Brandenburg Center for Regenerative Therapies (BCRT), Charité - Universitätsmedizin Berlin, Berlin 13353, Germany, nora-freyer@gmx.de.
  • Schneider C; Berlin Brandenburg Center for Regenerative Therapies (BCRT), Charité - Universitätsmedizin Berlin, Berlin 13353, Germany, nora-freyer@gmx.de.
  • Seehofer D; Department of Hepatobiliary Surgery and Visceral Transplantation, University of Leipzig, Leipzig 04103, Germany.
  • Stöhr T; PAION Deutschland GmbH (Non-clinical development), Aachen 52062, Germany.
  • Petersen KU; PAION Deutschland GmbH (Non-clinical development), Aachen 52062, Germany.
  • Zeilinger K; Berlin Brandenburg Center for Regenerative Therapies (BCRT), Charité - Universitätsmedizin Berlin, Berlin 13353, Germany, nora-freyer@gmx.de.
Drug Des Devel Ther ; 13: 1033-1047, 2019.
Article em En | MEDLINE | ID: mdl-31037028
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Benzodiazepinas / Reatores Biológicos / Hepatócitos Limite: Humans Idioma: En Revista: Drug Des Devel Ther Assunto da revista: FARMACOLOGIA / TERAPIA POR MEDICAMENTOS Ano de publicação: 2019 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Benzodiazepinas / Reatores Biológicos / Hepatócitos Limite: Humans Idioma: En Revista: Drug Des Devel Ther Assunto da revista: FARMACOLOGIA / TERAPIA POR MEDICAMENTOS Ano de publicação: 2019 Tipo de documento: Article