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A combined in silico and in vitro study on mouse Serpina1a antitrypsin-deficiency mutants.
Eggenschwiler, Reto; Patronov, Atanas; Hegermann, Jan; Fráguas-Eggenschwiler, Mariane; Wu, Guangming; Cortnumme, Leon; Ochs, Matthias; Antes, Iris; Cantz, Tobias.
Afiliação
  • Eggenschwiler R; Research Group Translational Hepatology and Stem Cell Biology, Cluster of Excellence REBIRTH, Hannover Medical School, Hannover, 30625, Germany. eggenschwiler.reto@mh-hannover.de.
  • Patronov A; Department of Gastroenterology, Hepatology and Endocrinology, Hannover Medical School, Hannover, 30625, Germany. eggenschwiler.reto@mh-hannover.de.
  • Hegermann J; Protein Modelling Group, Department of Life Sciences, Technical University Munich, Freising, 85354, Germany.
  • Fráguas-Eggenschwiler M; TUM School of Life Sciences, Center for Integrated Protein Science (CIPSM), Technical University Munich, Freising, 85354, Germany.
  • Wu G; Research Core Unit Electron Microscopy, Hannover Medical School, Hannover, 30625, Germany.
  • Cortnumme L; Institute of Functional and Applied Anatomy, Hannover Medical School, Hannover, 30625, Germany.
  • Ochs M; Imaging Platform of the Cluster of Excellence REBIRTH, Hannover Medical School, Hannover, 30625, Germany.
  • Antes I; Department of Gastroenterology, Hepatology and Endocrinology, Hannover Medical School, Hannover, 30625, Germany.
  • Cantz T; TWINCORE, Centre for Experimental and Clinical Infection Research, Hannover, 30625, Germany.
Sci Rep ; 9(1): 7486, 2019 05 16.
Article em En | MEDLINE | ID: mdl-31097772
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Alfa 1-Antitripsina / Deficiência de alfa 1-Antitripsina / Simulação de Dinâmica Molecular / Mutação com Perda de Função Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Revista: Sci Rep Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Alemanha
Texto completo
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Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Alfa 1-Antitripsina / Deficiência de alfa 1-Antitripsina / Simulação de Dinâmica Molecular / Mutação com Perda de Função Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Revista: Sci Rep Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Alemanha