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A novel, highly potent and selective phosphodiesterase-9 inhibitor for the treatment of sickle cell disease.
McArthur, James G; Svenstrup, Niels; Chen, Chunsheng; Fricot, Aurelie; Carvalho, Caroline; Nguyen, Julia; Nguyen, Phong; Parachikova, Anna; Abdulla, Fuad; Vercellotti, Gregory M; Hermine, Olivier; Edwards, Dave; Ribeil, Jean-Antoine; Belcher, John D; Maciel, Thiago T.
Afiliação
  • McArthur JG; Imara Inc., 2 Floor, 700 Technology Square, Cambridge, MA, USAImara Inc., 2 jmcarthur@cydanco.com.
  • Svenstrup N; H. Lundbeck A/S, Ottiliavej 9, 2500 Valby, Denmark.
  • Chen C; Department of Medicine, Division of Hematology, Oncology and Transplantation, University of Minnesota, Minneapolis, MN, USA.
  • Fricot A; INSERM UMR 1163, CNRS ERL 8254, Imagine Institute, Laboratory of Excellence GR-Ex, Paris Descartes - Sorbonne Paris Cité University, Paris, France.
  • Carvalho C; INSERM UMR 1163, CNRS ERL 8254, Imagine Institute, Laboratory of Excellence GR-Ex, Paris Descartes - Sorbonne Paris Cité University, Paris, France.
  • Nguyen J; Department of Medicine, Division of Hematology, Oncology and Transplantation, University of Minnesota, Minneapolis, MN, USA.
  • Nguyen P; Department of Medicine, Division of Hematology, Oncology and Transplantation, University of Minnesota, Minneapolis, MN, USA.
  • Parachikova A; H. Lundbeck A/S, Ottiliavej 9, 2500 Valby, Denmark.
  • Abdulla F; Department of Medicine, Division of Hematology, Oncology and Transplantation, University of Minnesota, Minneapolis, MN, USA.
  • Vercellotti GM; Department of Medicine, Division of Hematology, Oncology and Transplantation, University of Minnesota, Minneapolis, MN, USA.
  • Hermine O; INSERM UMR 1163, CNRS ERL 8254, Imagine Institute, Laboratory of Excellence GR-Ex, Paris Descartes - Sorbonne Paris Cité University, Paris, France.
  • Edwards D; Kinexum, 8830 Glen Ferry Drive, Johns Creek, GA, USA.
  • Ribeil JA; Departments of Biotherapy, Necker Children's Hospital, Assistance Publique-Hôpitaux de Paris (AP-HP), Paris Descartes- Sorbonne Paris Cité University, Paris, France.
  • Belcher JD; Department of Medicine, Division of Hematology, Oncology and Transplantation, University of Minnesota, Minneapolis, MN, USA.
  • Maciel TT; INSERM UMR 1163, CNRS ERL 8254, Imagine Institute, Laboratory of Excellence GR-Ex, Paris Descartes - Sorbonne Paris Cité University, Paris, France.
Haematologica ; 105(3): 623-631, 2020 03.
Article em En | MEDLINE | ID: mdl-31147439
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Inibidores de Fosfodiesterase / Anemia Falciforme Limite: Animals / Humans Idioma: En Revista: Haematologica Ano de publicação: 2020 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Inibidores de Fosfodiesterase / Anemia Falciforme Limite: Animals / Humans Idioma: En Revista: Haematologica Ano de publicação: 2020 Tipo de documento: Article