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Reactivation potency of two novel oximes (K456 and K733) against paraoxon-inhibited acetyl and butyrylcholinesterase: In silico and in vitro models.
Iqbal, Amna; Malik, Shahrukh; Nurulain, Syed M; Musilek, Kamil; Kuca, Kamil; Kalasz, Huba; Fatmi, M Qaiser.
Afiliação
  • Iqbal A; Department of Biosciences, COMSATS University Islamabad, Park Road, Chak Shahzad, Islamabad, 45600, Pakistan.
  • Malik S; Department of Biosciences, COMSATS University Islamabad, Park Road, Chak Shahzad, Islamabad, 45600, Pakistan.
  • Nurulain SM; Department of Biosciences, COMSATS University Islamabad, Park Road, Chak Shahzad, Islamabad, 45600, Pakistan.
  • Musilek K; University Hospital Hradec Kralove, Biomedical Research Center, Hradec Kralove, Czech Republic; University of Hradec Kralove, Faculty of Science, Department of Chemistry, Hradec Kralove, Czech Republic.
  • Kuca K; University of Hradec Kralove, Faculty of Science, Department of Chemistry, Hradec Kralove, Czech Republic.
  • Kalasz H; Semmelweis University, Budapest, Hungary.
  • Fatmi MQ; Department of Biosciences, COMSATS University Islamabad, Park Road, Chak Shahzad, Islamabad, 45600, Pakistan. Electronic address: qaiser.fatmi@comsats.edu.pk.
Chem Biol Interact ; 310: 108735, 2019 Sep 01.
Article em En | MEDLINE | ID: mdl-31276662
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Oximas / Paraoxon / Compostos de Piridínio / Inibidores da Colinesterase / Reativadores da Colinesterase Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Revista: Chem Biol Interact Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Paquistão
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Oximas / Paraoxon / Compostos de Piridínio / Inibidores da Colinesterase / Reativadores da Colinesterase Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Revista: Chem Biol Interact Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Paquistão