Histone methyltransferase SETDB1 promotes colorectal cancer proliferation through the STAT1-CCND1/CDK6 axis.

Yu, Lu; Ye, Feng; Li, Yi-Yi; Zhan, Yi-Zhi; Liu, Yang; Yan, Hong-Mei; Fang, Yuan; Xie, Yu-Wen; Zhang, Feng-Jiao; Chen, Long-Hua; Ding, Yi; Chen, Ke-Li

Yu, Lu; Ye, Feng; Li, Yi-Yi; Zhan, Yi-Zhi; Liu, Yang; Yan, Hong-Mei; Fang, Yuan; Xie, Yu-Wen; Zhang, Feng-Jiao; Chen, Long-Hua; Ding, Yi; Chen, Ke-Li.

Afiliação

Yu L; Department of Radiation Oncology, Nanfang Hospital, Southern Medical University, Guangzhou, China.
Ye F; Department of Radiation Oncology, Nanfang Hospital, Southern Medical University, Guangzhou, China.
Li YY; Department of Radiation Oncology, Nanfang Hospital, Southern Medical University, Guangzhou, China.
Zhan YZ; Department of Pathology, Nanfang Hospital, Southern Medical University, Guangzhou, China.
Liu Y; Department of Radiation Oncology, Nanfang Hospital, Southern Medical University, Guangzhou, China.
Yan HM; Department of Radiation Oncology, Nanfang Hospital, Southern Medical University, Guangzhou, China.
Fang Y; Department of Radiation Oncology, Nanfang Hospital, Southern Medical University, Guangzhou, China.
Xie YW; Department of Radiation Oncology, Nanfang Hospital, Southern Medical University, Guangzhou, China.
Zhang FJ; Department of Radiation Oncology, Nanfang Hospital, Southern Medical University, Guangzhou, China.
Chen LH; Department of Radiation Oncology, Nanfang Hospital, Southern Medical University, Guangzhou, China.
Ding Y; Department of Radiation Oncology, Nanfang Hospital, Southern Medical University, Guangzhou, China.
Chen KL; Department of Radiation Oncology, Nanfang Hospital, Southern Medical University, Guangzhou, China.

Carcinogenesis ; 41(5): 678-688, 2020 07 10.

Article em En | MEDLINE | ID: mdl-31306481

Assuntos

Biomarcadores Tumorais/metabolismo; Proliferação de Células; Neoplasias Colorretais/patologia; Ciclina D1/metabolismo; Quinase 6 Dependente de Ciclina/metabolismo; Histona-Lisina N-Metiltransferase/metabolismo; Fator de Transcrição STAT1/metabolismo; Animais; Apoptose; Biomarcadores Tumorais/genética; Movimento Celular; Neoplasias Colorretais/genética; Neoplasias Colorretais/metabolismo; Ciclina D1/genética; Quinase 6 Dependente de Ciclina/genética; Regulação Neoplásica da Expressão Gênica; Histona-Lisina N-Metiltransferase/genética; Humanos; Masculino; Camundongos; Camundongos Endogâmicos BALB C; Camundongos Nus; Fator de Transcrição STAT1/genética; Células Tumorais Cultivadas; Ensaios Antitumorais Modelo de Xenoenxerto

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias Colorretais / Biomarcadores Tumorais / Histona-Lisina N-Metiltransferase / Ciclina D1 / Proliferação de Células / Quinase 6 Dependente de Ciclina / Fator de Transcrição STAT1 Tipo de estudo: Prognostic_studies Limite: Animals / Humans / Male Idioma: En Revista: Carcinogenesis Ano de publicação: 2020 Tipo de documento: Article País de afiliação: China

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google