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Mitochondrial ROS-induced lysosomal dysfunction impairs autophagic flux and contributes to M1 macrophage polarization in a diabetic condition.
Yuan, Yujia; Chen, Younan; Peng, Tianqing; Li, Lan; Zhu, Wuzheng; Liu, Fei; Liu, Shuyun; An, Xingxing; Luo, Ruixi; Cheng, Jingqiu; Liu, Jingping; Lu, Yanrong.
Afiliação
  • Yuan Y; Key Laboratory of Transplant Engineering and Immunology, NHFPC, and Regenerative Medicine Research Center, West China Hospital, Sichuan University, Chengdu, China.
  • Chen Y; Key Laboratory of Transplant Engineering and Immunology, NHFPC, and Regenerative Medicine Research Center, West China Hospital, Sichuan University, Chengdu, China.
  • Peng T; Critical Illness Research, Lawson Health Research Institute, London Health Sciences Centre, London, Ontario, Canada.
  • Li L; Departments of Medicine and Pathology, University of Western Ontario, London, Ontario, Canada.
  • Zhu W; Key Laboratory of Transplant Engineering and Immunology, NHFPC, and Regenerative Medicine Research Center, West China Hospital, Sichuan University, Chengdu, China.
  • Liu F; Key Laboratory of Transplant Engineering and Immunology, NHFPC, and Regenerative Medicine Research Center, West China Hospital, Sichuan University, Chengdu, China.
  • Liu S; Key Laboratory of Transplant Engineering and Immunology, NHFPC, and Regenerative Medicine Research Center, West China Hospital, Sichuan University, Chengdu, China.
  • An X; Key Laboratory of Transplant Engineering and Immunology, NHFPC, and Regenerative Medicine Research Center, West China Hospital, Sichuan University, Chengdu, China.
  • Luo R; Key Laboratory of Transplant Engineering and Immunology, NHFPC, and Regenerative Medicine Research Center, West China Hospital, Sichuan University, Chengdu, China.
  • Cheng J; Key Laboratory of Transplant Engineering and Immunology, NHFPC, and Regenerative Medicine Research Center, West China Hospital, Sichuan University, Chengdu, China.
  • Liu J; Key Laboratory of Transplant Engineering and Immunology, NHFPC, and Regenerative Medicine Research Center, West China Hospital, Sichuan University, Chengdu, China.
  • Lu Y; Key Laboratory of Transplant Engineering and Immunology, NHFPC, and Regenerative Medicine Research Center, West China Hospital, Sichuan University, Chengdu, China luyanrong@scu.edu.cn liujingping@scu.edu.cn.
Clin Sci (Lond) ; 133(15): 1759-1777, 2019 08 15.
Article em En | MEDLINE | ID: mdl-31383716
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Autofagia / Polaridade Celular / Espécies Reativas de Oxigênio / Diabetes Mellitus Experimental / Lisossomos / Macrófagos / Mitocôndrias Limite: Animals / Humans / Male Idioma: En Revista: Clin Sci (Lond) Ano de publicação: 2019 Tipo de documento: Article País de afiliação: China
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Autofagia / Polaridade Celular / Espécies Reativas de Oxigênio / Diabetes Mellitus Experimental / Lisossomos / Macrófagos / Mitocôndrias Limite: Animals / Humans / Male Idioma: En Revista: Clin Sci (Lond) Ano de publicação: 2019 Tipo de documento: Article País de afiliação: China