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Paraneoplastic Hyperleukocytosis Mimicking Hematologic Malignancy Revealing a Localized Lung Cancer.
Marouf, Amira; Chapuis, Nicolas; Alary, Anne Sophie; Burroni, Barbara; Kosmider, Olivier; Alifano, Marco; Bouscary, Didier.
Afiliação
  • Marouf A; Université Paris Descartes, Faculté de Médecine, Sorbonne Paris Cité, Paris, France; Service d'Hématologie, Hôpital Cochin, Assistance Publique - Hôpitaux de Paris, Paris, France. Electronic address: amira.marouf@aphp.fr.
  • Chapuis N; Université Paris Descartes, Faculté de Médecine, Sorbonne Paris Cité, Paris, France; Service d'Hématologie Biologique, Hôpital Cochin, Assistance Publique - Hôpitaux de Paris, Paris, France; INSERM U1016, Institut Cochin, Paris, France.
  • Alary AS; Université Paris Descartes, Faculté de Médecine, Sorbonne Paris Cité, Paris, France; Service d'Hématologie Biologique, Hôpital Cochin, Assistance Publique - Hôpitaux de Paris, Paris, France.
  • Burroni B; Université Paris Descartes, Faculté de Médecine, Sorbonne Paris Cité, Paris, France; Service de Pathologie, Hôpital Cochin, Assistance Publique - Hôpitaux de Paris, Paris, France.
  • Kosmider O; Université Paris Descartes, Faculté de Médecine, Sorbonne Paris Cité, Paris, France; Service d'Hématologie Biologique, Hôpital Cochin, Assistance Publique - Hôpitaux de Paris, Paris, France; INSERM U1016, Institut Cochin, Paris, France.
  • Alifano M; Université Paris Descartes, Faculté de Médecine, Sorbonne Paris Cité, Paris, France; Service de Chirurgie Thoracique, Hôpital Cochin, Assistance Publique - Hôpitaux de Paris, Paris, France.
  • Bouscary D; Université Paris Descartes, Faculté de Médecine, Sorbonne Paris Cité, Paris, France; Service d'Hématologie, Hôpital Cochin, Assistance Publique - Hôpitaux de Paris, Paris, France; INSERM U1016, Institut Cochin, Paris, France.
Ann Thorac Surg ; 109(3): e203-e206, 2020 03.
Article em En | MEDLINE | ID: mdl-31408646
ABSTRACT
Paraneoplastic leukemoid reaction is a challenging differential diagnosis when it presents at the time of diagnosis of cancer. Severe hyperleukocytosis with elevation of blood neutrophils and monocytes counts can evoke myeloid hematologic malignancies. We report the case of a patient who presented with blood and bone marrow features highly suggestive of chronic myelomonocytic leukemia. The diagnosis of primary lung sarcomatoid carcinoma was performed. Surgical removal of this tumor which will always remain the priority led to full normalization of blood cell count.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Síndromes Paraneoplásicas / Leucemia Mielomonocítica Crônica / Reação Leucemoide / Neoplasias Pulmonares Tipo de estudo: Diagnostic_studies Limite: Humans / Male / Middle aged Idioma: En Revista: Ann Thorac Surg Ano de publicação: 2020 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Síndromes Paraneoplásicas / Leucemia Mielomonocítica Crônica / Reação Leucemoide / Neoplasias Pulmonares Tipo de estudo: Diagnostic_studies Limite: Humans / Male / Middle aged Idioma: En Revista: Ann Thorac Surg Ano de publicação: 2020 Tipo de documento: Article