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A High-Throughput Screen of a Library of Therapeutics Identifies Cytotoxic Substrates of P-glycoprotein.
Lee, Tobie D; Lee, Olivia W; Brimacombe, Kyle R; Chen, Lu; Guha, Rajarshi; Lusvarghi, Sabrina; Tebase, Bethilehem G; Klumpp-Thomas, Carleen; Robey, Robert W; Ambudkar, Suresh V; Shen, Min; Gottesman, Michael M; Hall, Matthew D.
Afiliação
  • Lee TD; National Center for Advancing Translational Sciences, National Institutes of Health, Rockville, Maryland (T.D.L., O.W.L., K.R.B., L.C., R.G., C.K.-T., M.S., M.D.H.) and Laboratory of Cell Biology, National Cancer Institute, National Institutes of Health, Bethesda, Maryland (S.L., B.G.T., R.W.R., S.V
  • Lee OW; National Center for Advancing Translational Sciences, National Institutes of Health, Rockville, Maryland (T.D.L., O.W.L., K.R.B., L.C., R.G., C.K.-T., M.S., M.D.H.) and Laboratory of Cell Biology, National Cancer Institute, National Institutes of Health, Bethesda, Maryland (S.L., B.G.T., R.W.R., S.V
  • Brimacombe KR; National Center for Advancing Translational Sciences, National Institutes of Health, Rockville, Maryland (T.D.L., O.W.L., K.R.B., L.C., R.G., C.K.-T., M.S., M.D.H.) and Laboratory of Cell Biology, National Cancer Institute, National Institutes of Health, Bethesda, Maryland (S.L., B.G.T., R.W.R., S.V
  • Chen L; National Center for Advancing Translational Sciences, National Institutes of Health, Rockville, Maryland (T.D.L., O.W.L., K.R.B., L.C., R.G., C.K.-T., M.S., M.D.H.) and Laboratory of Cell Biology, National Cancer Institute, National Institutes of Health, Bethesda, Maryland (S.L., B.G.T., R.W.R., S.V
  • Guha R; National Center for Advancing Translational Sciences, National Institutes of Health, Rockville, Maryland (T.D.L., O.W.L., K.R.B., L.C., R.G., C.K.-T., M.S., M.D.H.) and Laboratory of Cell Biology, National Cancer Institute, National Institutes of Health, Bethesda, Maryland (S.L., B.G.T., R.W.R., S.V
  • Lusvarghi S; National Center for Advancing Translational Sciences, National Institutes of Health, Rockville, Maryland (T.D.L., O.W.L., K.R.B., L.C., R.G., C.K.-T., M.S., M.D.H.) and Laboratory of Cell Biology, National Cancer Institute, National Institutes of Health, Bethesda, Maryland (S.L., B.G.T., R.W.R., S.V
  • Tebase BG; National Center for Advancing Translational Sciences, National Institutes of Health, Rockville, Maryland (T.D.L., O.W.L., K.R.B., L.C., R.G., C.K.-T., M.S., M.D.H.) and Laboratory of Cell Biology, National Cancer Institute, National Institutes of Health, Bethesda, Maryland (S.L., B.G.T., R.W.R., S.V
  • Klumpp-Thomas C; National Center for Advancing Translational Sciences, National Institutes of Health, Rockville, Maryland (T.D.L., O.W.L., K.R.B., L.C., R.G., C.K.-T., M.S., M.D.H.) and Laboratory of Cell Biology, National Cancer Institute, National Institutes of Health, Bethesda, Maryland (S.L., B.G.T., R.W.R., S.V
  • Robey RW; National Center for Advancing Translational Sciences, National Institutes of Health, Rockville, Maryland (T.D.L., O.W.L., K.R.B., L.C., R.G., C.K.-T., M.S., M.D.H.) and Laboratory of Cell Biology, National Cancer Institute, National Institutes of Health, Bethesda, Maryland (S.L., B.G.T., R.W.R., S.V
  • Ambudkar SV; National Center for Advancing Translational Sciences, National Institutes of Health, Rockville, Maryland (T.D.L., O.W.L., K.R.B., L.C., R.G., C.K.-T., M.S., M.D.H.) and Laboratory of Cell Biology, National Cancer Institute, National Institutes of Health, Bethesda, Maryland (S.L., B.G.T., R.W.R., S.V
  • Shen M; National Center for Advancing Translational Sciences, National Institutes of Health, Rockville, Maryland (T.D.L., O.W.L., K.R.B., L.C., R.G., C.K.-T., M.S., M.D.H.) and Laboratory of Cell Biology, National Cancer Institute, National Institutes of Health, Bethesda, Maryland (S.L., B.G.T., R.W.R., S.V
  • Gottesman MM; National Center for Advancing Translational Sciences, National Institutes of Health, Rockville, Maryland (T.D.L., O.W.L., K.R.B., L.C., R.G., C.K.-T., M.S., M.D.H.) and Laboratory of Cell Biology, National Cancer Institute, National Institutes of Health, Bethesda, Maryland (S.L., B.G.T., R.W.R., S.V
  • Hall MD; National Center for Advancing Translational Sciences, National Institutes of Health, Rockville, Maryland (T.D.L., O.W.L., K.R.B., L.C., R.G., C.K.-T., M.S., M.D.H.) and Laboratory of Cell Biology, National Cancer Institute, National Institutes of Health, Bethesda, Maryland (S.L., B.G.T., R.W.R., S.V
Mol Pharmacol ; 96(5): 629-640, 2019 11.
Article em En | MEDLINE | ID: mdl-31515284
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Membro 1 da Subfamília B de Cassetes de Ligação de ATP / Citotoxinas / Ensaios de Triagem em Larga Escala / Membro 2 da Subfamília G de Transportadores de Cassetes de Ligação de ATP / Proteínas de Neoplasias Limite: Humans Idioma: En Revista: Mol Pharmacol Ano de publicação: 2019 Tipo de documento: Article País de afiliação: El Salvador
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Membro 1 da Subfamília B de Cassetes de Ligação de ATP / Citotoxinas / Ensaios de Triagem em Larga Escala / Membro 2 da Subfamília G de Transportadores de Cassetes de Ligação de ATP / Proteínas de Neoplasias Limite: Humans Idioma: En Revista: Mol Pharmacol Ano de publicação: 2019 Tipo de documento: Article País de afiliação: El Salvador