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Structural basis of ligand selectivity and disease mutations in cysteinyl leukotriene receptors.
Gusach, Anastasiia; Luginina, Aleksandra; Marin, Egor; Brouillette, Rebecca L; Besserer-Offroy, Élie; Longpré, Jean-Michel; Ishchenko, Andrii; Popov, Petr; Patel, Nilkanth; Fujimoto, Taku; Maruyama, Toru; Stauch, Benjamin; Ergasheva, Margarita; Romanovskaia, Daria; Stepko, Anastasiia; Kovalev, Kirill; Shevtsov, Mikhail; Gordeliy, Valentin; Han, Gye Won; Katritch, Vsevolod; Borshchevskiy, Valentin; Sarret, Philippe; Mishin, Alexey; Cherezov, Vadim.
Afiliação
  • Gusach A; Research Сenter for Molecular Mechanisms of Aging and Age-Related Diseases, Moscow Institute of Physics and Technology, Dolgoprudny, Russia, 141701.
  • Luginina A; Research Сenter for Molecular Mechanisms of Aging and Age-Related Diseases, Moscow Institute of Physics and Technology, Dolgoprudny, Russia, 141701.
  • Marin E; Research Сenter for Molecular Mechanisms of Aging and Age-Related Diseases, Moscow Institute of Physics and Technology, Dolgoprudny, Russia, 141701.
  • Brouillette RL; Department of Pharmacology-Physiology, Faculty of Medicine and Health Sciences, Institut de Pharmacologie de Sherbrooke, Université de Sherbrooke, Sherbrooke, QC, J1H 5N4, Canada.
  • Besserer-Offroy É; Department of Pharmacology-Physiology, Faculty of Medicine and Health Sciences, Institut de Pharmacologie de Sherbrooke, Université de Sherbrooke, Sherbrooke, QC, J1H 5N4, Canada.
  • Longpré JM; Department of Pharmacology-Physiology, Faculty of Medicine and Health Sciences, Institut de Pharmacologie de Sherbrooke, Université de Sherbrooke, Sherbrooke, QC, J1H 5N4, Canada.
  • Ishchenko A; Bridge Institute, Michelson Center for Convergent Bioscience, University of Southern California, Los Angeles, CA, 90089, USA.
  • Popov P; Department of Chemistry, University of Southern California, Los Angeles, CA, 90089, USA.
  • Patel N; Merck Research Laboratories, Merck & Co Inc., 770 Sumneytown Pike, West Point, PA, 19486, USA.
  • Fujimoto T; Research Сenter for Molecular Mechanisms of Aging and Age-Related Diseases, Moscow Institute of Physics and Technology, Dolgoprudny, Russia, 141701.
  • Maruyama T; Center for Computational and Data Intensive Science and Engineering, Skolkovo Institute of Science and Technology, Bolshoy Boulevard 30, Building 1, Moscow, Russia, 121205.
  • Stauch B; Bridge Institute, Michelson Center for Convergent Bioscience, University of Southern California, Los Angeles, CA, 90089, USA.
  • Ergasheva M; Department of Biological Sciences, University of Southern California, Los Angeles, CA, 90089, USA.
  • Romanovskaia D; Ono Pharmaceutical Co., Ltd., 3-1-1 Sakurai, Shimamoto, Mishima, Osaka, 618-8585, Japan.
  • Stepko A; Ono Pharmaceutical Co., Ltd., 3-1-1 Sakurai, Shimamoto, Mishima, Osaka, 618-8585, Japan.
  • Kovalev K; Bridge Institute, Michelson Center for Convergent Bioscience, University of Southern California, Los Angeles, CA, 90089, USA.
  • Shevtsov M; Department of Chemistry, University of Southern California, Los Angeles, CA, 90089, USA.
  • Gordeliy V; Research Сenter for Molecular Mechanisms of Aging and Age-Related Diseases, Moscow Institute of Physics and Technology, Dolgoprudny, Russia, 141701.
  • Han GW; Research Сenter for Molecular Mechanisms of Aging and Age-Related Diseases, Moscow Institute of Physics and Technology, Dolgoprudny, Russia, 141701.
  • Katritch V; CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences, 1090, Vienna, Austria.
  • Borshchevskiy V; Research Сenter for Molecular Mechanisms of Aging and Age-Related Diseases, Moscow Institute of Physics and Technology, Dolgoprudny, Russia, 141701.
  • Sarret P; Research Сenter for Molecular Mechanisms of Aging and Age-Related Diseases, Moscow Institute of Physics and Technology, Dolgoprudny, Russia, 141701.
  • Mishin A; Institute of Complex Systems (ICS), ICS-6: Structural Biochemistry, Research Center Jülich, Jülich, Germany.
  • Cherezov V; Institut de Biologie Structurale Jean-Pierre Ebel, Université Grenoble Alpes-Commissariat à l'Energie Atomique et aux Energies Alternatives-CNRS, Grenoble, France.
Nat Commun ; 10(1): 5573, 2019 12 06.
Article em En | MEDLINE | ID: mdl-31811124
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Receptores de Leucotrienos / Mutação Limite: Animals / Humans Idioma: En Revista: Nat Commun Assunto da revista: BIOLOGIA / CIENCIA Ano de publicação: 2019 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Receptores de Leucotrienos / Mutação Limite: Animals / Humans Idioma: En Revista: Nat Commun Assunto da revista: BIOLOGIA / CIENCIA Ano de publicação: 2019 Tipo de documento: Article