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Genome sequences of chikungunya virus isolates from an outbreak in southwest Bangkok in 2018.
Chansaenroj, Jira; Wanlapakorn, Nasamon; Ngamsaithong, Chokchai; Thongmee, Thanunrat; Na Nakorn, Natthaphon; Siriyasatien, Padet; Vongpunsawad, Sompong; Poovorawan, Yong.
Afiliação
  • Chansaenroj J; Department of Pediatrics, Faculty of Medicine, Center of Excellence in Clinical Virology, Chulalongkorn University, Bangkok, 10330, Thailand.
  • Wanlapakorn N; Department of Pediatrics, Faculty of Medicine, Center of Excellence in Clinical Virology, Chulalongkorn University, Bangkok, 10330, Thailand.
  • Ngamsaithong C; Division of Academic Affairs, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand.
  • Thongmee T; Health Center 29, Health Department, Bangkok Metropolitan Administration, Bangkok, Thailand.
  • Na Nakorn N; Department of Pediatrics, Faculty of Medicine, Center of Excellence in Clinical Virology, Chulalongkorn University, Bangkok, 10330, Thailand.
  • Siriyasatien P; Faculty of Medical Technology, Prince of Songkhla University, Hat Yai, Songkhla, Thailand.
  • Vongpunsawad S; Vector Biology and Vector-Borne Disease Research Unit, Department of Parasitology, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand.
  • Poovorawan Y; Department of Pediatrics, Faculty of Medicine, Center of Excellence in Clinical Virology, Chulalongkorn University, Bangkok, 10330, Thailand.
Arch Virol ; 165(2): 445-450, 2020 Feb.
Article em En | MEDLINE | ID: mdl-31834526
ABSTRACT
An outbreak of chikungunya virus (CHIKV) infection occurred in southwest Bangkok during the 2018 rainy season. The envelope glycoprotein E1 gene sequence of the infecting strain belonged to an East/Central/South African lineage with alanine at residue 226. Mutations in the predicted E1 (K211E) and E2 (V264A) proteins of CHIKV were identified in CHIKV-infected patients and in an Aedes aegypti mosquito. Analysis of the complete genome sequences showed marked differences from the strains causing previous outbreaks in Thailand in 2008-2009 and 2013 but showed similarities to strains from more recent CHIKV outbreaks in South and Southeast Asia.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Vírus Chikungunya / Febre de Chikungunya Limite: Animals / Female / Humans País/Região como assunto: Asia Idioma: En Revista: Arch Virol Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Tailândia
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Vírus Chikungunya / Febre de Chikungunya Limite: Animals / Female / Humans País/Região como assunto: Asia Idioma: En Revista: Arch Virol Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Tailândia