Phosphoenolpyruvate from Glycolysis and PEPCK Regulate Cancer Cell Fate by Altering Cytosolic Ca<sup>2</sup>.

Moreno-Felici, Juan; Hyrossová, Petra; Aragó, Marc; Rodríguez-Arévalo, Sergio; García-Rovés, Pablo M; Escolano, Carmen; Perales, Jose C

Phosphoenolpyruvate from Glycolysis and PEPCK Regulate Cancer Cell Fate by Altering Cytosolic Ca².

Moreno-Felici, Juan; Hyrossová, Petra; Aragó, Marc; Rodríguez-Arévalo, Sergio; García-Rovés, Pablo M; Escolano, Carmen; Perales, Jose C.

Afiliação

Moreno-Felici J; Department of Physiological Sciences, School of Medicine, University of Barcelona, Feixa Llarga s/n, 08907 L'Hospitalet del Llobregat, Barcelona, Spain.
Hyrossová P; Department of Physiological Sciences, School of Medicine, University of Barcelona, Feixa Llarga s/n, 08907 L'Hospitalet del Llobregat, Barcelona, Spain.
Aragó M; Department of Physiological Sciences, School of Medicine, University of Barcelona, Feixa Llarga s/n, 08907 L'Hospitalet del Llobregat, Barcelona, Spain.
Rodríguez-Arévalo S; Laboratory of Medicinal Chemistry (Associated Unit to CSIC), Faculty of Pharmacy and Food Sciences, and Institute of Biomedicine (IBUB), University of Barcelona, 08028 Barcelona, Spain.
García-Rovés PM; Department of Physiological Sciences, School of Medicine, University of Barcelona, Feixa Llarga s/n, 08907 L'Hospitalet del Llobregat, Barcelona, Spain.
Escolano C; Laboratory of Medicinal Chemistry (Associated Unit to CSIC), Faculty of Pharmacy and Food Sciences, and Institute of Biomedicine (IBUB), University of Barcelona, 08028 Barcelona, Spain.
Perales JC; Department of Physiological Sciences, School of Medicine, University of Barcelona, Feixa Llarga s/n, 08907 L'Hospitalet del Llobregat, Barcelona, Spain.

Cells ; 9(1)2019 12 19.

Article em En | MEDLINE | ID: mdl-31861674

Assuntos

Cálcio/metabolismo; Neoplasias do Colo/metabolismo; Citosol/metabolismo; Fosfoenolpiruvato Carboxiquinase (ATP)/metabolismo; Fosfoenolpiruvato/farmacologia; Sinalização do Cálcio; Linhagem Celular Tumoral; Ciclo-Oxigenase 2/genética; Regulação Neoplásica da Expressão Gênica/efeitos dos fármacos; Glicólise; Células HCT116; Humanos; Interleucina-6/genética; Fatores de Transcrição NFATC; Proteínas Proto-Oncogênicas c-myc/genética

Palavras-chave

CaMK2G; NFAT; PCK2; PEPCK-M; TCA cycle; c-Myc; calcium; cancer metabolism; cataplerosis; phosphoenolpyruvate; phosphoenolpyruvate carboxykinase; phosphoenolpyruvate carboxykinase (PEPCK); sarcoplasmic reticulum Ca2+/ATPase pump (SERCA)

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Fosfoenolpiruvato / Cálcio / Neoplasias do Colo / Fosfoenolpiruvato Carboxiquinase (ATP) / Citosol Limite: Humans Idioma: En Revista: Cells Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Espanha

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google