IL6 inhibition of inflammatory S100A8/9 proteins is NF-&#954;B mediated in essential thrombocythemia.

Diklic, Milos; Mitrovic-Ajtic, Olivera; Suboticki, Tijana; Djikic, Dragoslava; Kovacic, Marijana; Bjelica, Suncica; Beleslin-Cokic, Bojana; Tosic, Milica; Lekovic, Danijela; Gotic, Mirjana; Santibanez, Juan F; Cokic, Vladan P

IL6 inhibition of inflammatory S100A8/9 proteins is NF-κB mediated in essential thrombocythemia.

Diklic, Milos; Mitrovic-Ajtic, Olivera; Suboticki, Tijana; Djikic, Dragoslava; Kovacic, Marijana; Bjelica, Suncica; Beleslin-Cokic, Bojana; Tosic, Milica; Lekovic, Danijela; Gotic, Mirjana; Santibanez, Juan F; Cokic, Vladan P.

Afiliação

Diklic M; Department of Molecular Oncology, Institute for Medical Research, University of Belgrade, Belgade, Serbia.
Mitrovic-Ajtic O; Department of Molecular Oncology, Institute for Medical Research, University of Belgrade, Belgade, Serbia.
Suboticki T; Department of Molecular Oncology, Institute for Medical Research, University of Belgrade, Belgade, Serbia.
Djikic D; Department of Molecular Oncology, Institute for Medical Research, University of Belgrade, Belgade, Serbia.
Kovacic M; Department of Molecular Oncology, Institute for Medical Research, University of Belgrade, Belgade, Serbia.
Bjelica S; Department of Molecular Oncology, Institute for Medical Research, University of Belgrade, Belgade, Serbia.
Beleslin-Cokic B; Clinic for Endocrinology, Diabetes and Metabolic Diseases, Genetic Laboratory, Clinical Center of Serbia, Belgrade, Serbia.
Tosic M; Department of Molecular Oncology, Institute for Medical Research, University of Belgrade, Belgade, Serbia.
Lekovic D; Clinic of Hematology, Clinical Center of Serbia, Belgrade, Serbia.
Gotic M; School of Medicine, University of Belgrade, Belgrade, Serbia.
Santibanez JF; Clinic of Hematology, Clinical Center of Serbia, Belgrade, Serbia.
Cokic VP; School of Medicine, University of Belgrade, Belgrade, Serbia.

Cell Biochem Funct ; 38(4): 362-372, 2020 Jun.

Article em En | MEDLINE | ID: mdl-31885098

Assuntos

Calgranulina A/metabolismo; Calgranulina B/metabolismo; Interleucina-6/metabolismo; Leucócitos Mononucleares/metabolismo; NF-kappa B/metabolismo; Transdução de Sinais; Trombocitemia Essencial/metabolismo; Substituição de Aminoácidos; Calgranulina A/genética; Calgranulina B/genética; Feminino; Humanos; Interleucina-6/genética; Janus Quinase 2/genética; Janus Quinase 2/metabolismo; Leucócitos Mononucleares/patologia; Masculino; Mutação de Sentido Incorreto; NF-kappa B/genética; Fosfatidilinositol 3-Quinases/genética; Fosfatidilinositol 3-Quinases/metabolismo; Trombocitemia Essencial/genética; Trombocitemia Essencial/patologia

Palavras-chave

G2/M phase; NF-κB signalling; S100A8/9; interleukin 10; interleukin 6; myeloproliferative neoplasm

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Leucócitos Mononucleares / Transdução de Sinais / NF-kappa B / Interleucina-6 / Calgranulina A / Calgranulina B / Trombocitemia Essencial Limite: Female / Humans / Male Idioma: En Revista: Cell Biochem Funct Ano de publicação: 2020 Tipo de documento: Article

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google