14-3-3 proteins protect AMPK-phosphorylated ten-eleven translocation-2 (TET2) from PP2A-mediated dephosphorylation.

Kundu, Anirban; Shelar, Sandeep; Ghosh, Arindam P; Ballestas, Mary; Kirkman, Richard; Nam, Hyeyoung; Brinkley, Garrett J; Karki, Suman; Mobley, James A; Bae, Sejong; Varambally, Sooryanarayana; Sudarshan, Sunil

Kundu, Anirban; Shelar, Sandeep; Ghosh, Arindam P; Ballestas, Mary; Kirkman, Richard; Nam, Hyeyoung; Brinkley, Garrett J; Karki, Suman; Mobley, James A; Bae, Sejong; Varambally, Sooryanarayana; Sudarshan, Sunil.

Afiliação

Kundu A; Department of Urology, University of Alabama, Birmingham, Alabama 35294.
Shelar S; Department of Urology, University of Alabama, Birmingham, Alabama 35294.
Ghosh AP; Department of Urology, University of Alabama, Birmingham, Alabama 35294.
Ballestas M; Department of Genetics, University of Alabama, Birmingham, Alabama 35294.
Kirkman R; Department of Urology, University of Alabama, Birmingham, Alabama 35294.
Nam H; Department of Urology, University of Alabama, Birmingham, Alabama 35294.
Brinkley GJ; Department of Urology, University of Alabama, Birmingham, Alabama 35294.
Karki S; Department of Urology, University of Alabama, Birmingham, Alabama 35294.
Mobley JA; Department of Anesthesiology and Perioperative Medicine, University of Alabama, Birmingham, Alabama 35294.
Bae S; Department of Medicine, University of Alabama, Birmingham, Alabama 35294.
Varambally S; Department of Pathology, University of Alabama, Birmingham, Alabama 35294.
Sudarshan S; Department of Urology, University of Alabama, Birmingham, Alabama 35294; Birmingham Veterans Affairs Medical Center, Birmingham, Alabama 35233. Electronic address: sudarshan@uab.edu.

J Biol Chem ; 295(6): 1754-1766, 2020 02 07.

Article em En | MEDLINE | ID: mdl-31901078

Assuntos

Proteínas 14-3-3/metabolismo; Proteínas Quinases Ativadas por AMP/metabolismo; Proteínas de Ligação a DNA/metabolismo; Proteína Fosfatase 2/metabolismo; Proteínas Proto-Oncogênicas/metabolismo; Animais; Dioxigenases; Células HEK293; Humanos; Camundongos; Fosforilação; Ligação Proteica; Isoformas de Proteínas/metabolismo

Palavras-chave

14-3-3; 5-hydroxymethylcytosine (5hmC); AMP-activated protein kinase (AMPK); Post-translational modification; dioxygenase; epigenetics; gene regulation; phosphorylation; protein phosphatase 2A (PP2A); ten-eleven-translocation-2 (TET2)

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proteínas Proto-Oncogênicas / Proteínas 14-3-3 / Proteínas de Ligação a DNA / Proteína Fosfatase 2 / Proteínas Quinases Ativadas por AMP Limite: Animals / Humans Idioma: En Revista: J Biol Chem Ano de publicação: 2020 Tipo de documento: Article

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