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Rapid non-uniform adaptation to conformation-specific KRAS(G12C) inhibition.
Xue, Jenny Y; Zhao, Yulei; Aronowitz, Jordan; Mai, Trang T; Vides, Alberto; Qeriqi, Besnik; Kim, Dongsung; Li, Chuanchuan; de Stanchina, Elisa; Mazutis, Linas; Risso, Davide; Lito, Piro.
Afiliação
  • Xue JY; Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
  • Zhao Y; Tri-Institutional MD-PhD Program, Weill Cornell Medical College and Rockefeller University and Memorial Sloan Kettering Cancer Center, New York, NY, USA.
  • Aronowitz J; Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
  • Mai TT; Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
  • Vides A; Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
  • Qeriqi B; Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
  • Kim D; Antitumor Assessment Core Facility, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
  • Li C; Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
  • de Stanchina E; Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
  • Mazutis L; Antitumor Assessment Core Facility, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
  • Risso D; Computational and Systems Biology, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
  • Lito P; Department of Statistical Sciences, University of Padova, Padua, Italy.
Nature ; 577(7790): 421-425, 2020 01.
Article em En | MEDLINE | ID: mdl-31915379
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proteínas Proto-Oncogênicas p21(ras) / Mutação Limite: Humans Idioma: En Revista: Nature Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Estados Unidos
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proteínas Proto-Oncogênicas p21(ras) / Mutação Limite: Humans Idioma: En Revista: Nature Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Estados Unidos